1-Fluoronaphthalene

Modify Date: 2024-01-02 05:51:03

1-Fluoronaphthalene structure	Common Name	1-Fluoronaphthalene
	CAS Number	321-38-0	Molecular Weight	146.161
	Density	1.1±0.1 g/cm3	Boiling Point	215.0±0.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₇F	Melting Point	−13 °C(lit.)
	MSDS	Chinese USA	Flash Point	65.6±0.0 °C
	Symbol	GHS08	Signal Word	Warning

Use of 1-Fluoronaphthalene

1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake[1].

Name	Fluoronaphthalene
Synonym	More Synonyms

Description	1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	1-Fluoronaphthalene (3 mg, 24 h) can be oxidized by C.elegans ATCC 36112 to form trans-3,4-dihydroxy-3,4-dihydro-1-fluoronaphthalene and trans-5,6-dihydroxy-5,6-dihydro-1-fluoronaphthalene and to form 1-fluoro-8-hydroxy-5-tetralone, 5-hydroxy-1-fluoronaphthalene and 4-hydroxy-1-fluoronaphthalene as well as glucosides, sulfates and glucuronide conjugates of these phenols[1].
References	[1]. C E Cerniglia, et al. Effects of a fluoro substituent on the fungal metabolism of 1-fluoronaphthalene. Appl Environ Microbiol. 1984 Aug;48(2):294-300.

Density	1.1±0.1 g/cm3
Boiling Point	215.0±0.0 °C at 760 mmHg
Melting Point	−13 °C(lit.)
Molecular Formula	C₁₀H₇F
Molecular Weight	146.161
Flash Point	65.6±0.0 °C
Exact Mass	146.053177
LogP	3.50
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.606
Stability	Stable. Incompatible with strong oxidizing agents.

1-Fluoronaphthalene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ7100000

CHEMICAL NAME :: Naphthalene, 1-fluoro-

CAS REGISTRY NUMBER :: 321-38-0

BEILSTEIN REFERENCE NO. :: 1906413

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H7-F

MOLECULAR WEIGHT :: 146.17

WISWESSER LINE NOTATION :: L66J BF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 22,1133,1937 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4416 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H351
Precautionary Statements	P281
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S36/37-S24/25-S23-S53
RIDADR	UN 2810
WGK Germany	3
RTECS	QJ7100000
HS Code	2903999090

Precursor 9
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DownStream 10
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HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Synthesis of highly oxygenated dinaphthyl ethers via SNAr reactions promoted by Barton's base.

Org. Lett. 5(7) , 1155-8, (2003)

[reaction: see text] Electron-rich dinaphthyl ethers were synthesized by S(N)Ar reactions between naphthols and activated fluoronaphthalenes. 2-tert-Butyl-1,1,3,3-tetramethylguanidine (Barton's base) ...

Effects of a fluoro substituent on the fungal metabolism of 1-fluoronaphthalene.

Appl. Environ. Microbiol. 48(2) , 294-300, (1984)

The metabolism of 1-fluoronaphthalene by Cunninghamella elegans ATCC 36112 was studied. The metabolites were isolated by reverse-phase high-pressure liquid chromatography and characterized by the appl...

A one-pot access to 6-substituted phenanthridines from fluoroarenes and nitriles via 1,2-arynes.

Org. Lett. 4(16) , 2687-90, (2002)

[reaction: see text] A one-pot, t-BuLi-induced synthesis of 6-substituted phenanthridines from fluoroarenes and nitriles via 1,2-arynes is reported. Aryl- and hetaryl nitriles, cyanamides, and trimeth...

1-FLUORONAPTHALENE

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EINECS 206-287-0

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MFCD00003873

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1-FLUORO NAPHTHALENE

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1-Fluoronaphthalene
Price: ￥348.0/100g ￥118.0/25g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fluoronaphthalene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 1-Fluoronaphthalene
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Fluoronaphthalene
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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1-Fluoronaphthalene

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