MLS000545091
Modify Date: 2026-03-25 14:41:39
MLS000545091 structure
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Common Name | MLS000545091 | ||
|---|---|---|---|---|
| CAS Number | 322666-76-2 | Molecular Weight | 262.73 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H15ClN2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MLS000545091MLS000545091 is a potent and selective lipoxygenase-2 (LOX-2) inhibitor with an IC50 value of 2.6 μM for h15-LOX-2[1]. |
| Name | 1,3,4-Oxadiazole, 2-(4-chlorophenyl)-5-cyclohexyl |
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| Description | MLS000545091 is a potent and selective lipoxygenase-2 (LOX-2) inhibitor with an IC50 value of 2.6 μM for h15-LOX-2[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C14H15ClN2O |
|---|---|
| Molecular Weight | 262.73 |
| InChIKey | ASRSXDRAEGLYDZ-UHFFFAOYSA-N |
| SMILES | Clc1ccc(-c2nnc(C3CCCCC3)o2)cc1 |
| Storage condition | -20°C |
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: NCATS Kinetic Aqueous Solubility Profiling
Source: NCGC
Target: N/A
External Id: ADME-solubility1
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Confirmatory qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12...
Source: NCGC
External Id: 12hLO-f-round2
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: NCATS Parallel Artificial Membrane Permeability Assay (PAMPA) Profiling
Source: NCGC
Target: N/A
External Id: ADME-PAMPA1
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