3-Chlorogentisyl alcohol
3-Chlorogentisyl alcohol structure
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Common Name | 3-Chlorogentisyl alcohol | ||
|---|---|---|---|---|
| CAS Number | 32744-80-2 | Molecular Weight | 174.58200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H7ClO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3-Chlorogentisyl alcohol3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 µM, an Ki value of 0.58 µM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies[1]. |
| Name | chlorogentisyl alcohol |
|---|---|
| Synonym | More Synonyms |
| Description | 3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 µM, an Ki value of 0.58 µM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies[1]. |
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| Related Catalog | |
| Target |
IC50: 0.74 µM (β-glucuronidase)[1] |
| In Vitro | 3-Chlorogentisyl alcohol (compound 1) (20 µM; 24 h) shows antiproliferative activity in Namalwa, U266 cells[1]. Cell Proliferation Assay[1] Cell Line: Namalwa, U266 cells Concentration: 20 µM Incubation Time: 24 h Result: Showed antiproliferative activity with the viability rate of 70.40% and 94.08% in Namalwa, U266 cells, respectively. |
| References |
| Molecular Formula | C7H7ClO3 |
|---|---|
| Molecular Weight | 174.58200 |
| Exact Mass | 174.00800 |
| PSA | 60.69000 |
| LogP | 1.32750 |
| InChIKey | GUIGFYWMQAYTBT-UHFFFAOYSA-N |
| SMILES | OCc1cc(O)cc(Cl)c1O |
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3-Chlorogentisy... CAS#:32744-80-2 |
| Literature: McCorkindale,N.J. et al. Tetrahedron, 1972 , vol. 28, p. 1107 - 1111 |
|
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3-Chlorogentisy... CAS#:32744-80-2 |
| Literature: McCorkindale,N.J. et al. Tetrahedron, 1972 , vol. 28, p. 1107 - 1111 |
|
~%
3-Chlorogentisy... CAS#:32744-80-2 |
| Literature: McCorkindale,N.J. et al. Tetrahedron, 1972 , vol. 28, p. 1107 - 1111 |
|
~%
3-Chlorogentisy... CAS#:32744-80-2 |
| Literature: McCorkindale,N.J. et al. Tetrahedron, 1972 , vol. 28, p. 1107 - 1111 |
|
~%
3-Chlorogentisy... CAS#:32744-80-2 |
| Literature: Sequin-Frey,M.; Tamm,C. Helvetica Chimica Acta, 1971 , vol. 54, # 3 p. 851 - 861 |
|
~%
3-Chlorogentisy... CAS#:32744-80-2 |
| Literature: Sequin-Frey,M.; Tamm,C. Helvetica Chimica Acta, 1971 , vol. 54, # 3 p. 851 - 861 |
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Name: Antiproliferative activity against human U266B cells assessed as cell viability at 20...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5353057
|
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Name: Antiproliferative activity against human NAMALVA cells assessed as cell viability at ...
Source: ChEMBL
Target: NAMALVA
External Id: CHEMBL5353056
|
|
Name: Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay
Source: ChEMBL
Target: HT-29
External Id: CHEMBL4119185
|
|
Name: Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay
Source: ChEMBL
Target: MCF7
External Id: CHEMBL4119184
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Name: Non-competitive inhibition of Escherichia coli beta-glucuronidase assessed as reducti...
Source: ChEMBL
Target: Beta-glucuronidase
External Id: CHEMBL5353050
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