2-Chloro-N-(4-chlorophenyl)acetamide

Modify Date: 2026-07-01 20:16:00

2-Chloro-N-(4-chlorophenyl)acetamide structure	Common Name	2-Chloro-N-(4-chlorophenyl)acetamide
	CAS Number	3289-75-6	Molecular Weight	204.05
	Density	1.4±0.1 g/cm3	Boiling Point	368.8±27.0 °C at 760 mmHg
	Molecular Formula	C₈H₇Cl₂NO	Melting Point	168ºC
	MSDS	N/A	Flash Point	176.8±23.7 °C

Use of 2-Chloro-N-(4-chlorophenyl)acetamide

2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL[1].

Summary: 2-Chloro-N-(4-chlorophenyl)acetamide (Chinese name: N-(4-氯苯基)-2-氯乙酰胺, CAS number: 3289-75-6) is an organic compound with molecular formula C8H7Cl2NO and molecular weight 204.05. It melts at 168°C and has a boiling point of 368.8±27.0°C, with a density of 1.4±0.1 g/cm3. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	2-chloro-N-(4-chlorophenyl)acetamide
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Yamazoe H, et al. [Studies on the experimental chemotherapy of dermatomycosis and candidiasis. V. On the antifungal activity for various arylhaloacetamide compounds in vitro and in vivo]. Yakugaku Zasshi. 1968 Dec;88(12):1602-9. Japanese.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.4±0.1 g/cm3
Boiling Point	368.8±27.0 °C at 760 mmHg
Melting Point	168ºC
Molecular Formula	C₈H₇Cl₂NO
Molecular Weight	204.05
Flash Point	176.8±23.7 °C
Exact Mass	202.990463
PSA	29.10000
LogP	2.60
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.606
InChIKey	UDRCRMHFHHTVSN-UHFFFAOYSA-N
SMILES	O=C(CCl)Nc1ccc(Cl)cc1

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

2-Chloro-N-(4-chlorophenyl)acetamide MSDS(Chinese)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36/37/39
HS Code	2924299090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

4-Chloroaniline

CAS#:106-47-8

Chloroacetyl ch...

CAS#:79-04-9

~98%

2-Chloro-N-(4-c...

CAS#:3289-75-6

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Literature: Virsis, I. E.; Silaraya, D. A.; Grinberga, B. A.; Prikulis, A. A.; Gerbashevska, I. D.; Orenish, M. E. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 12 p. 849 - 853 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 12 p. 23 - 26

2-chloroacetyl ...

CAS#:19103-78-7

4-Chloroaniline

CAS#:106-47-8

2-Chloro-N-(4-c...

CAS#:3289-75-6

Learn More

Literature: Die Pharmazie, , vol. 23, # 10 p. 561 - 566

Sulfuric acid

CAS#:7664-93-9

α-chloromethyl ...

CAS#:140854-26-8

2-Chloro-N-(4-c...

CAS#:3289-75-6

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Literature: Bulletin de la Societe Chimique de France, , vol. <3> 27, p. 542

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 5
CAS#:106-47-8 4-Chloroaniline CAS#:79-04-9 Chloroacetyl ch... CAS#:19103-78-7 2-chloroacetyl ... CAS#:7664-93-9 Sulfuric acid
CAS#:140854-26-8 α-chloromethyl ...
DownStream 10
CAS#:108086-47-1 N-(4-chlorophen... CAS#:101-88-2 N-(4-Chlorophen... CAS#:861797-55-9 iminodi-acetic ... CAS#:20265-96-7 4-Chloroaniline...
CAS#:17630-75-0 5-Chlorooxindole CAS#:124476-84-2 4,6-diamino-1-(... CAS#:124476-80-8 2-AMINO-1-(4-CH... CAS#:74487-97-1 N'-(4-CHLORO-PH...
CAS#:65446-95-9 N-(4-chlorophen... CAS#:65685-00-9 N-(4-chlorophen...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1040691

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose

Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose

Name: NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compoun...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1040694

Name: NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in er...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1040692

Name: NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction ...
Source: ChEMBL
Target: Plasmodium yoelii
External Id: CHEMBL1789905

Name: NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL1040693

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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2-CHLORO-N-(4-CHLORO-PHENYL)-ACETAMIDE

[(4-chlorophenyl)aminocarbonylmethyl]chloride

2-chloro-N-(p-chlorophenyl)acetamide

F1791-1505

2-chloro-N-(4-chlorophenyl)-acetamide

N1-(4-Chlorophenyl)-2-Chloroacetamide

MFCD00018904

GNF-Pf-1811

2-Chloro-N-(4-chlorophenyl)acetamide

2,4-dichloro-acetanilide

N-(4-Chlorophenyl)-2-chloroacetamide

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of 2-chloro-N-(4-chlorophenyl)acetamide?

A: Polar surface area (PSA) of 2-chloro-N-(4-chlorophenyl)acetamide is 29.10000.

Q: What is the CAS number of 2-chloro-N-(4-chlorophenyl)acetamide?

A: CAS number of 2-chloro-N-(4-chlorophenyl)acetamide is 3289-75-6.

Q: What is the boiling point of 2-chloro-N-(4-chlorophenyl)acetamide?

A: Boiling point of 2-chloro-N-(4-chlorophenyl)acetamide is 368.8±27.0 °C at 760 mmHg.

Q: What are the upstream materials of 2-chloro-N-(4-chlorophenyl)acetamide?

A: Related upstream materials(CAS) of 2-chloro-N-(4-chlorophenyl)acetamide: 106-47-8;79-04-9;19103-78-7;7664-93-9;140854-26-8.

Q: What is the InChIKey of 2-chloro-N-(4-chlorophenyl)acetamide?

A: InChIKey of 2-chloro-N-(4-chlorophenyl)acetamide is UDRCRMHFHHTVSN-UHFFFAOYSA-N.

Q: What is the molecular weight of 2-chloro-N-(4-chlorophenyl)acetamide?

A: Molecular weight of 2-chloro-N-(4-chlorophenyl)acetamide is 204.05.

Q: What is the melting point of 2-chloro-N-(4-chlorophenyl)acetamide?

A: Melting point of 2-chloro-N-(4-chlorophenyl)acetamide is 168ºC.

Q: What are the uses of 2-chloro-N-(4-chlorophenyl)acetamide?

A: Main uses of 2-chloro-N-(4-chlorophenyl)acetamide: 2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL[1].

Q: What are the downstream products of 2-chloro-N-(4-chlorophenyl)acetamide?

A: Related downstream products(CAS) of 2-chloro-N-(4-chlorophenyl)acetamide: 108086-47-1;101-88-2;861797-55-9;20265-96-7;17630-75-0;124476-84-2;124476-80-8;74487-97-1;65446-95-9;65685-00-9.

Q: What is the SMILES notation of 2-chloro-N-(4-chlorophenyl)acetamide?

A: SMILES notation of 2-chloro-N-(4-chlorophenyl)acetamide is O=C(CCl)Nc1ccc(Cl)cc1.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Chloro-N-(4-chlorophenyl)acetamide
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-(4-Chlorophenyl)-2-chloroacetamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥100/100 mg

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