2-Chloro-N-(4-chlorophenyl)acetamide

Modify Date: 2025-08-27 11:04:46

2-Chloro-N-(4-chlorophenyl)acetamide Structure
2-Chloro-N-(4-chlorophenyl)acetamide structure
Common Name 2-Chloro-N-(4-chlorophenyl)acetamide
CAS Number 3289-75-6 Molecular Weight 204.05
Density 1.4±0.1 g/cm3 Boiling Point 368.8±27.0 °C at 760 mmHg
Molecular Formula C8H7Cl2NO Melting Point 168ºC
MSDS N/A Flash Point 176.8±23.7 °C

 Use of 2-Chloro-N-(4-chlorophenyl)acetamide


2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL[1].

 Names

Name 2-chloro-N-(4-chlorophenyl)acetamide
Synonym More Synonyms

 2-Chloro-N-(4-chlorophenyl)acetamide Biological Activity

Description 2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL[1].
Related Catalog
References

[1]. Yamazoe H, et al. [Studies on the experimental chemotherapy of dermatomycosis and candidiasis. V. On the antifungal activity for various arylhaloacetamide compounds in vitro and in vivo]. Yakugaku Zasshi. 1968 Dec;88(12):1602-9. Japanese.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 368.8±27.0 °C at 760 mmHg
Melting Point 168ºC
Molecular Formula C8H7Cl2NO
Molecular Weight 204.05
Flash Point 176.8±23.7 °C
Exact Mass 202.990463
PSA 29.10000
LogP 2.60
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.606
InChIKey UDRCRMHFHHTVSN-UHFFFAOYSA-N
SMILES O=C(CCl)Nc1ccc(Cl)cc1

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
HS Code 2924299090

 Synthetic Route

~98%

2-Chloro-N-(4-chlorophenyl)acetamide Structure

2-Chloro-N-(4-c...

CAS#:3289-75-6

Literature: Virsis, I. E.; Silaraya, D. A.; Grinberga, B. A.; Prikulis, A. A.; Gerbashevska, I. D.; Orenish, M. E. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 12 p. 849 - 853 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 12 p. 23 - 26

~%

2-Chloro-N-(4-chlorophenyl)acetamide Structure

2-Chloro-N-(4-c...

CAS#:3289-75-6

Literature: Die Pharmazie, , vol. 23, # 10 p. 561 - 566

~%

2-Chloro-N-(4-chlorophenyl)acetamide Structure

2-Chloro-N-(4-c...

CAS#:3289-75-6

Literature: Bulletin de la Societe Chimique de France, , vol. <3> 27, p. 542

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 2-Chloro-N-(4-chlorophenyl)acetamideBioassay

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Name: NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1040691
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
Name: NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compoun...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1040694
Name: NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in er...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1040692
Name: NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction ...
Source: ChEMBL
Target: Plasmodium yoelii
External Id: CHEMBL1789905
Name: NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL1040693
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 Synonyms

2-CHLORO-N-(4-CHLORO-PHENYL)-ACETAMIDE
[(4-chlorophenyl)aminocarbonylmethyl]chloride
2-chloro-N-(p-chlorophenyl)acetamide
F1791-1505
2-chloro-N-(4-chlorophenyl)-acetamide
N1-(4-Chlorophenyl)-2-Chloroacetamide
MFCD00018904
GNF-Pf-1811
2-Chloro-N-(4-chlorophenyl)acetamide
2,4-dichloro-acetanilide
N-(4-Chlorophenyl)-2-chloroacetamide
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