InS3-54
Modify Date: 2024-01-13 19:07:16
InS3-54 structure
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Common Name | InS3-54 | ||
|---|---|---|---|---|
| CAS Number | 328998-92-1 | Molecular Weight | 412.401 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H16N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of InS3-54An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3, without affecting the activation and dimerization of STAT3; preferentially suppresses proliferation of cancer over non-cancer cells and inhibits migration and invasion of malignant cells; selectively inhibits STAT3 binding to DNA without affecting the activation and dimerization of STAT3; inhibits expression of STAT3 downstream target genes and STAT3 binding to chromatin in situ. |
| Name | InS3-54 |
|---|
| Description | An STAT3 inhibitor that selectively targets the DNA-binding domain of STAT3, without affecting the activation and dimerization of STAT3; preferentially suppresses proliferation of cancer over non-cancer cells and inhibits migration and invasion of malignant cells; selectively inhibits STAT3 binding to DNA without affecting the activation and dimerization of STAT3; inhibits expression of STAT3 downstream target genes and STAT3 binding to chromatin in situ. |
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| References | References 1. Huang W, et al. ACS Chem Biol. 2014 May 16;9(5):1188-96. 2. Huang W, et al. Oncogene. 2016 Feb 11;35(6):783-92. View Related Products by Target STAT |
| Molecular Formula | C24H16N2O5 |
|---|---|
| Molecular Weight | 412.401 |