Epinephrine Hydrochloride

Modify Date: 2025-08-20 12:33:18

Epinephrine Hydrochloride Structure
Epinephrine Hydrochloride structure
 Common Name Epinephrine Hydrochloride
CAS Number 329-63-5 Molecular Weight 219.665
Density 1.283 g/cm3 Boiling Point 413.1ºC at 760 mmHg
Molecular Formula C9H14ClNO3 Melting Point N/A
MSDS Chinese USA Flash Point 207.9ºC
Symbol GHS06
GHS06		 Signal Word Danger

 Names

Name dl-adrenaline hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.283 g/cm3
Boiling Point 413.1ºC at 760 mmHg
Molecular Formula C9H14ClNO3
Molecular Weight 219.665
Flash Point 207.9ºC
Exact Mass 219.066223
PSA 72.72000
LogP 1.54350
Stability Stable, but light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
Water Solubility H2O: >50 mg/mL

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DO3330000
CHEMICAL NAME :
Benzyl alcohol, 3,4-dihydroxy-alpha-((methylamino)methyl)-, hydrochloride, (+-)-
CAS REGISTRY NUMBER :
329-63-5
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C9-H13-N-O3.Cl-H
MOLECULAR WEIGHT :
219.69
WISWESSER LINE NOTATION :
QR BQ DYQ1M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,1705,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
70 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,1705,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,1705,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 92,369,1948
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 92,108,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3132 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 207 (estimated) No. of Female Employees: 69 (estimated)

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H311-H315-H319-H335
Precautionary Statements P261-P280-P301 + P310-P305 + P351 + P338-P312
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T: Toxic;
Risk Phrases R24/25
Safety Phrases S26-S36/37-S45
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS DO3330000
Packaging Group II
Hazard Class 6.1(a)
HS Code 2922509090

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles5

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 Epinephrine HydrochlorideBioassay

View more

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Confirmed inhibitors of the Choline Transporter (CHT)
Source: 1043
Target: high affinity choline transporter 1 [Homo sapiens]
External Id: SAID_488997
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
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 Synonyms

[3H]-(+/-)-Epinephrine hydrochloride
DL-EPINEPHRINE HYDROCHLORIDE
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol hydrochloride
rs-epinephrine hcl
Racepinephrine/Adrenaline HCL
(+/-)-EPINEPHRINE HYDROCHLORIDE
(+/-)-adrenaline hydrochloride
(-)-3,4-DIHYDROXY-α-((METHYLAMINO)METHYL)BENZYL ALCOHOL HYDROCHLORIDE
(+/-)-ADRENALIN HYDROCHLORIDE
MFCD00050562
4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol hydrochloride (1:1)
epinephrine HCl
RAC EPINEPHRINE HCL
(R/S)-adrenaline hydrochloride
l-1-(3,4-dihydroxyphenyl)-2-methylamino-1-ethanol hydrochloride
1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochloride (1:1)
UNII:336096P2WE
EINECS 206-346-0
4-[1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol hydrochloride (1:1)
Diaceton-alpha-D-mannofuranose
Epinephrine Hydrochloride
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