5'-Phosphoguanylyl-(3',5')-guanosine

Modify Date: 2024-01-16 12:24:23

5'-Phosphoguanylyl-(3',5')-guanosine Structure
5'-Phosphoguanylyl-(3',5')-guanosine structure
 Common Name 5'-Phosphoguanylyl-(3',5')-guanosine
CAS Number 33008-99-0 Molecular Weight 708.42600
Density N/A Boiling Point N/A
Molecular Formula C20H26N10O15P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5'-Phosphoguanylyl-(3',5')-guanosine


5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids[1][2].

 Names

Name 5'-phosphoguanylyl-(3'->5')-guanosine
Synonym More Synonyms

 5'-Phosphoguanylyl-(3',5')-guanosine Biological Activity

Description 5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids[1][2].
Related Catalog
In Vitro 5'-Phosphoguanylyl-(3',5')-guanosine reduces the rate of c-di-GMP degradation in cell lysates and inhibits the activity of EAL-dependent PDEs (PA2133, PvrR, and purified recombinant RocR) from P. aeruginosa[2].
References

[1]. Nesbitt NM, et, al. Modification of a bi-functional diguanylate cyclase-phosphodiesterase to efficiently produce cyclic diguanylate monophosphate. Biotechnol Rep (Amst). 2015 May 5;7:30-37.

[2]. Cohen D, et, al. Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11359-64.

 Chemical & Physical Properties

Molecular Formula C20H26N10O15P2
Molecular Weight 708.42600
Exact Mass 708.10500
PSA 400.47000

 Synonyms

pG3'p5'G
pG3'pG
guanylyl-(5'->3')-[5']guanylic acid
Guanylyl(3'->5')guanin
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Chemsrc provides 5'-Phosphoguanylyl-(3',5')-guanosine(CAS#:33008-99-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 5'-Phosphoguanylyl-(3',5')-guanosine are included as well.>> amp version: 5'-Phosphoguanylyl-(3',5')-guanosine

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