5'-Phosphoguanylyl-(3',5')-guanosine

Modify Date: 2024-01-16 12:24:23

5'-Phosphoguanylyl-(3',5')-guanosine structure	Common Name	5'-Phosphoguanylyl-(3',5')-guanosine
	CAS Number	33008-99-0	Molecular Weight	708.42600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₆N₁₀O₁₅P₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5'-Phosphoguanylyl-(3',5')-guanosine

5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids[1][2].

Name	5'-phosphoguanylyl-(3'->5')-guanosine
Synonym	More Synonyms

Description	5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	5'-Phosphoguanylyl-(3',5')-guanosine reduces the rate of c-di-GMP degradation in cell lysates and inhibits the activity of EAL-dependent PDEs (PA2133, PvrR, and purified recombinant RocR) from P. aeruginosa[2].
References	[1]. Nesbitt NM, et, al. Modification of a bi-functional diguanylate cyclase-phosphodiesterase to efficiently produce cyclic diguanylate monophosphate. Biotechnol Rep (Amst). 2015 May 5;7:30-37. [2]. Cohen D, et, al. Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11359-64.

Molecular Formula	C₂₀H₂₆N₁₀O₁₅P₂
Molecular Weight	708.42600
Exact Mass	708.10500
PSA	400.47000

pG3'p5'G

pG3'pG

guanylyl-(5'->3')-[5']guanylic acid

Guanylyl(3'->5')guanin

5'-Phosphoguanylyl-(3',5')-guanosine

Use of 5'-Phosphoguanylyl-(3',5')-guanosine

Names

5'-Phosphoguanylyl-(3',5')-guanosine Biological Activity

Chemical & Physical Properties

Synonyms