Adalimumab

Modify Date: 2025-08-21 10:30:21

Adalimumab Structure
Adalimumab structure
Common Name Adalimumab
CAS Number 331731-18-1 Molecular Weight 434.46288
Density N/A Boiling Point N/A
Molecular Formula C6428H9912N1694O1987S46 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Adalimumab


Adalimumab (anti-TNF-α) is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

 Names

Name Unii-fys6T7F842

 Adalimumab Biological Activity

Description Adalimumab (anti-TNF-α) is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
Related Catalog
In Vitro Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab (anti-TNF-α) than used in this study[2].
In Vivo The elimination half-life (t1/2) of Adalimumab (anti-TNF-α) is long (~20 days)[1]. The enriched fluorescent-labelled adalimumab (anti-TNF-α) is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr-/- mice[2].
References

[1]. Ternant D, et al. Pharmacokinetics and concentration-effect relationship of adalimumab in rheumatoid arthritis. Br J Clin Pharmacol. 2015 Feb;79(2):286-97.

[2]. Oberoi R, et al. Targeting Tumor Necrosis Factor-α with Adalimumab: Effects on Endothelial Activation and Monocyte Adhesion. PLoS One. 2016 Jul 28;11(7):e0160145.

 Chemical & Physical Properties

Molecular Formula C6428H9912N1694O1987S46
Molecular Weight 434.46288
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Adalimumab suppliers

Adalimumab price