Spermidine trihydrochloride

Modify Date: 2025-08-21 09:16:24

Spermidine trihydrochloride Structure
Spermidine trihydrochloride structure
 Common Name Spermidine trihydrochloride
CAS Number 334-50-9 Molecular Weight 254.629
Density 0.906 g/cm3 Boiling Point 246.6ºC at 760 mmHg
Molecular Formula C7H22Cl3N3 Melting Point 257-259 °C(lit.)
MSDS USA Flash Point 118.1ºC
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Spermidine trihydrochloride


Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents[1].

 Names

Name N'-(3-aminopropyl)butane-1,4-diamine,trihydrochloride
Synonym More Synonyms

 Spermidine trihydrochloride Biological Activity

Description Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents[1].
Related Catalog
In Vitro Spermidine plays a crucial role of against abiotic stresses, such as salt, drought, heat, and salinity-alkalinity stresses in tomato, cucumber, rice[1].
References

[1]. Zhang L, et al.  The Alleviation of Heat Damage to Photosystem II and Enzymatic Antioxidants by Exogenous Spermidine in Tall Fescue. Front Plant Sci. 2017 Oct 12;8:1747.

 Chemical & Physical Properties

Density 0.906 g/cm3
Boiling Point 246.6ºC at 760 mmHg
Melting Point 257-259 °C(lit.)
Molecular Formula C7H22Cl3N3
Molecular Weight 254.629
Flash Point 118.1ºC
Exact Mass 253.087936
PSA 64.07000
LogP 3.86120
InChIKey WRROLJSGZKCWGR-UHFFFAOYSA-N
SMILES Cl.NCCCCNCCCN
Storage condition 2-8°C
Water Solubility H2O: 1 M at 20 °C, clear, colorless

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EJ7023000
CHEMICAL NAME :
1,4-Butanediamine, N-(3-aminopropyl)-, trihydrochloride
CAS REGISTRY NUMBER :
334-50-9
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H19-N3.3Cl-H
MOLECULAR WEIGHT :
254.67
WISWESSER LINE NOTATION :
Z4M3Z &GH 3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
870 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 41,1575,1982

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS EJ7023000
HS Code 2921290000

 Customs

HS Code 2921290000
Summary 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles3

More Articles
Interaction of myo-inositol hexakisphosphate with biogenic and synthetic polyamines.

Org. Biomol. Chem. 13 , 7500-12, (2015)

Within all the eukaryotic cells myo-inositol phosphates (InsPs) are an important group of biomolecules that are potentially related to signaling functions. The most abundant member of this family in n...

Effect of Novel Starter Culture on Reduction of Biogenic Amines, Quality Improvement, and Sensory Properties of Doenjang, a Traditional Korean Soybean Fermented Sauce Variety.

J. Food Sci. 80 , M1794-803, (2015)

To select appropriate microorganisms as starter cultures for the reliable and reproducible fermentation of soybean fermented products of Korean Doenjang, various ratios of fungi (Aspergillus oryzae J,...

HPLC-UV method validation for the identification and quantification of bioactive amines in commercial eggs.

Talanta 142 , 240-5, (2015)

A quantitative and confirmatory high-performance liquid chromatography with ultraviolet detection (HPLC-UV) method for the determination of bioactive amines in the albumen and yolk of commercial eggs ...

 Spermidine trihydrochlorideBioassay

View more

Name: qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay vali...
Source: NCGC
External Id: adst_MBL_Abs_LOPAC_o1
Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: qHTS assay for measurement of the activity of small molecule inhibitors on Zika virus...
Source: NCGC
Target: N/A
External Id: ZIK097
Name: Tocris HTS for Inhibitors of Aerobactin Synthetase lucA
Source: 23265
External Id: IucA Pilot Assay Tocris Library
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
Name: Validation qHTS for Identification of Calcium Integrin Binding protein 1 (CIB1) Compe...
Source: NCGC
External Id: cib1-v1-fp-lopac
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
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 Synonyms

SPD trihydrochloride
N1-(3-Aminopropyl)butane-1,4-diamine trihydrochloride
N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
1,4-Butanediamine, N-(3-aminopropyl)-, hydrochloride (1:3)
Spermidine hydrochloride
4-Azoniaoctamethylenediammonium trichloride
Spermidine,Trihydrochloride
MFCD00012918
n-(3-aminopropyl)butane-1,4-diamine trihydrochloride
N-(3-aminopropyl)-1,4-butanediamine, trihydrochloride
N-(3-aminopropyl)butane-1,4-diaminetrihydrochloride
Spermidine trihydrochloride
EINECS 206-379-0
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