N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide

Modify Date: 2025-08-31 11:51:17

N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide structure	Common Name	N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide
	CAS Number	339-44-6	Molecular Weight	309.34100
	Density	1.354g/cm3	Boiling Point	515.1ºC at 760mmHg
	Molecular Formula	C₁₃H₁₅N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	265.4ºC

Use of N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide

Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus[1].

Name	N-[5-(2-methoxyethoxy)pyrimidin-2-yl]benzenesulfonamide
Synonym	More Synonyms

Description	Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Glymidine. Br Med J. 1967;2(5555):817.

Density	1.354g/cm3
Boiling Point	515.1ºC at 760mmHg
Molecular Formula	C₁₃H₁₅N₃O₄S
Molecular Weight	309.34100
Flash Point	265.4ºC
Exact Mass	309.07800
PSA	98.79000
LogP	2.45640
Index of Refraction	1.588
InChIKey	QFWPJPIVLCBXFJ-UHFFFAOYSA-N
SMILES	COCCOc1cnc(NS(=O)(=O)c2ccccc2)nc1

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB2910000

CHEMICAL NAME :: Benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-

CAS REGISTRY NUMBER :: 339-44-6

BEILSTEIN REFERENCE NO. :: 0552655

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H15-N3-O4-S

MOLECULAR WEIGHT :: 309.37

WISWESSER LINE NOTATION :: T6N CNJ BMSWR& EO201

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3100 mg/kg

TOXIC EFFECTS :: Endocrine - hypoglycemia

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,377,1964

HS Code	2935009090

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Name: Binding affinity towards human ADRA2A in an in vitro assay with cellular components m...
Source: ChEMBL
Target: Alpha-2A adrenergic receptor
External Id: CHEMBL5291736

Name: Binding affinity towards human GABRA1 in an in vitro assay with cellular components m...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit gamma-2
External Id: CHEMBL5291799

Name: Binding affinity towards human PGR in an in vitro assay with cellular components meas...
Source: ChEMBL
Target: Progesterone receptor
External Id: CHEMBL5291863

Name: Antagonist activity at human ADRA1A in an in vitro cell-based assay measured by fluor...
Source: ChEMBL
Target: Alpha-1A adrenergic receptor
External Id: CHEMBL5291731

Name: Binding affinity towards human ESR1 in an in vitro cell free assay (CRO assay) measur...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL5291792

Name: Binding affinity towards human ADORA3 (agonistic activity) in an in vitro assay with ...
Source: ChEMBL
Target: Adenosine receptor A3
External Id: CHEMBL5291728

Name: Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay m...
Source: ChEMBL
Target: cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
External Id: CHEMBL5291856

Name: Binding affinity towards human OPRM1 in an in vitro assay with cellular components me...
Source: ChEMBL
Target: Mu-type opioid receptor
External Id: CHEMBL5291855

Name: Agonist activity at human ADRA1A in an in vitro cell-based assay (CRO assay) measured...
Source: ChEMBL
Target: Alpha-1A adrenergic receptor
External Id: CHEMBL5291730

Name: Compound was evaluated for inhibition of human F2 in an in vitro cell free assay meas...
Source: ChEMBL
Target: Prothrombin
External Id: CHEMBL5291794

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Glycodiazin

Glycodiazin [German]

EINECS 206-426-5

N-[5-(2-methoxy-ethoxy)-pyrimidin-2-yl]-benzenesulfonamide

GLYMIDINE

UNII-4C5I4BQZ8F

Glymidinum

Glycodiazine

Glidiazine

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Product Name: N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide
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Purity: 98.0%
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Use of N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.