L-3-Pyrroline-2-carboxylic acid

Modify Date: 2024-01-08 19:18:46

L-3-Pyrroline-2-carboxylic acid Structure
L-3-Pyrroline-2-carboxylic acid structure
Common Name L-3-Pyrroline-2-carboxylic acid
CAS Number 3395-35-5 Molecular Weight 113.115
Density 1.3±0.1 g/cm3 Boiling Point 279.3±40.0 °C at 760 mmHg
Molecular Formula C5H7NO2 Melting Point 245ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 122.7±27.3 °C

 Use of L-3-Pyrroline-2-carboxylic acid


3,4-Dehydro-DL-proline is a proline derivative[1].

 Names

Name 3,4-dehydro-dl-proline
Synonym More Synonyms

 L-3-Pyrroline-2-carboxylic acid Biological Activity

Description 3,4-Dehydro-DL-proline is a proline derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 279.3±40.0 °C at 760 mmHg
Melting Point 245ºC (dec.)(lit.)
Molecular Formula C5H7NO2
Molecular Weight 113.115
Flash Point 122.7±27.3 °C
Exact Mass 113.047676
PSA 49.33000
LogP 0.10
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.521
Storage condition -15°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases R22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

~76%

L-3-Pyrroline-2-carboxylic acid Structure

L-3-Pyrroline-2...

CAS#:3395-35-5

Literature: Synthetic Communications, , vol. 10, # 7 p. 529 - 540

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles25

More Articles
Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation.

J. Biol. Chem. 279(53) , 55051-9, (2004)

Three human prolyl 4-hydroxylases (P4Hs) regulate the hypoxia-inducible transcription factors (HIFs) by hydroxylating a Leu-Xaa-Xaa-Leu-Ala-Pro motif. We report here that the two leucines in the Leu-G...

Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro.

Arterioscler. Thromb. Vasc. Biol. 24(1) , 67-72, (2004)

Overexpression of decorin reduces neointimal thickening in balloon-injured carotid arteries of rats by decreasing the volume of neointimal extracellular matrix (ECM). We examined the hypothesis that d...

Enhanced and feedback-resistant gamma-glutamyl kinase activity of an Escherichia coli transformant carrying a mutated proB gene of Streptococcus thermophilus.

FEMS Microbiol. Lett. 182(1) , 143-7, (2000)

We used a PCR-based method to generate a single base pair mutation in the proB gene of Streptococcus thermophilus, which replaced an aspartic acid with a glycine residue at position 192 of the first p...

 Synonyms

3,4-Dehydro-DL-proline
3,4-dehydro-D,L-proline
H-DL-PRO(3,4-DEHYDRO)-OH
3,4-DIDEHYDRO-DL-PROLINE
L-3-Pyrroline-2-carboxylic acid
rac-(2R*)-3-Pyrroline-2-carboxylic acid
EINECS 222-243-3
R,S-3,4-dehydroproline
2,5-Dihydro-1H-pyrrole-2-carboxylic acid
H-DL-DELTAPRO-OH
H-3,4-DEHYDRO-DL-PRO-OH
D,L-3,4-dehydroproline
1H-Pyrrole-2-carboxylic acid, 2,5-dihydro-
3,4-Dedihydro-DL-proline
3,4-Dehydro-DL-prolin
(+/-)-3-PYRROLINE-2-CARBOXYLIC ACID
2,5-dihydro-pyrrole-2-carboxylic acid
3,4-Dedihydroproline
MFCD00005214