7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole

Modify Date: 2024-01-13 18:06:07

7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole Structure
7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole structure
Common Name 7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole
CAS Number 33984-50-8 Molecular Weight 300.26900
Density 1.438 g/cm3 Boiling Point 500.8ºC at 760 mmHg
Molecular Formula C14H12N4O4 Melting Point 178-182ºC
MSDS Chinese USA Flash Point 256.7ºC

 Use of 7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole


MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule[1][2].

 Names

Name N-[(4-methoxyphenyl)methyl]-4-nitro-2,1,3-benzoxadiazol-7-amine
Synonym More Synonyms

  Biological Activity

Description MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule[1][2].
Related Catalog
References

[1]. Kenner RA, et al. A new fluorescent probe for protein and nucleoprotein conformation. Binding of 7-(p-methoxybenzylamino)-4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes. Biochemistry. 1971;10(24):4433-4440.

[2]. Kasahara Y, et al. Formation of a conformationally changed C1r, a subcomponent of the first component of human complement, as an intermediate of its autoactivation reaction. FEBS Lett. 1982;141(1):128-131.

 Chemical & Physical Properties

Density 1.438 g/cm3
Boiling Point 500.8ºC at 760 mmHg
Melting Point 178-182ºC
Molecular Formula C14H12N4O4
Molecular Weight 300.26900
Flash Point 256.7ºC
Exact Mass 300.08600
PSA 106.00000
LogP 3.34790
Index of Refraction 1.691

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

Benzofurazan,4-((p-methoxybenzyl)amino)-7-nitro
4-(4-Methoxybenzylamino)-7-nitrobenzofurazan
t56 bnonj fnw im1r do1[wln]
s-benzofurazanamine,N-[(4-methoxyphenyl)methyl]-7-nitro
4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole
7-(p-Methoxybenzylamino)-4-nitrobenz-2-oxa-1,3-diazol
4-(4-methoxybenzylamino)-7-nitrobenzofurazane
MFCD00042778
4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole,MBD
EINECS 251-775-9
MBD
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