AX-000

Modify Date: 2025-09-12 16:03:57

AX-000 Structure
AX-000 structure
Common Name AX-000
CAS Number 340014-88-2 Molecular Weight 381.519
Density N/A Boiling Point N/A
Molecular Formula C27H27NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AX-000


A hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

 Names

Name AX-000

 AX-000 Biological Activity

Description A hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.
References References 1. Borroto A, et al. Sci Transl Med. 2016 Dec 21;8(370):370ra184. View Related Products by Target T Cell Receptor (TCR)

 Chemical & Physical Properties

Molecular Formula C27H27NO
Molecular Weight 381.519
InChIKey GWYDJCJGEAPHBM-UHFFFAOYSA-N
SMILES c1ccc(C2=C(CN3CCCCC3)C(c3ccccc3)c3ccccc3O2)cc1
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