4,4′-difluorobenzophenone

Modify Date: 2026-06-30 18:29:44

4,4′-difluorobenzophenone structure	Common Name	4,4′-difluorobenzophenone
	CAS Number	345-92-6	Molecular Weight	218.199
	Density	1.2±0.1 g/cm3	Boiling Point	308.8±27.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₈F₂O	Melting Point	102-105 °C(lit.)
	MSDS	Chinese USA	Flash Point	118.4±17.9 °C
	Symbol	GHS07, GHS09	Signal Word	Warning

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	bis(4-fluorophenyl)methanone
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.2±0.1 g/cm3
Boiling Point	308.8±27.0 °C at 760 mmHg
Melting Point	102-105 °C(lit.)
Molecular Formula	C₁₃H₈F₂O
Molecular Weight	218.199
Flash Point	118.4±17.9 °C
Exact Mass	218.054321
PSA	17.07000
LogP	3.62
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.550
InChIKey	LSQARZALBDFYQZ-UHFFFAOYSA-N
SMILES	O=C(c1ccc(F)cc1)c1ccc(F)cc1

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

4,4′-difluorobenzophenone MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ0685000

CHEMICAL NAME :: Benzophenone, 4,4'-difluoro-

CAS REGISTRY NUMBER :: 345-92-6

BEILSTEIN REFERENCE NO. :: 0516231

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H8-F2-O

MOLECULAR WEIGHT :: 218.21

WISWESSER LINE NOTATION :: FR DVR DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04689

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335-H411
Precautionary Statements	P261-P273-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	UN 3077 9 / PGIII
WGK Germany	3
RTECS	DJ0685000
Packaging Group	I; II; III
HS Code	2914700090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:1093981-40-8 4,4'-(azidometh... CAS#:1765-93-1 4-Fluorobenzene... CAS#:403-43-0 4-FLUOROBENZOYL... CAS#:365-24-2 4,4'-Difluroben...
CAS#:457-68-1 Bis(4-fluorophe... CAS#:90-98-2 4,4'-Dichlorobe... CAS#:67-71-0 Dimethyl sulfone CAS#:459-57-4 4-Fluorobenzaldehyde
CAS#:3988-03-2 4,4'-Dibromoben... CAS#:79-37-8 Oxalyl chloride
DownStream 10
CAS#:457-68-1 Bis(4-fluorophe... CAS#:456-22-4 4-Fluorobenzoic acid CAS#:379-57-7 4,4',4''-Triflu... CAS#:16574-54-2 [4-(dimethylami...
CAS#:90-94-8 Michler's ketone CAS#:198889-20-2 3,3-bis(4-fluor... CAS#:365-24-2 4,4'-Difluroben... CAS#:90-96-0 DMBP
CAS#:345-89-1 4-fluoro-4'-met... CAS#:345-90-4 1,1'-(Bromometh...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2914700090
Summary	HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Oxidative metabolism of flunarizine in rat liver microsomes.

Res. Commun. Chem. Pathol. Pharmacol. 78(1) , 85-95, (1992)

The oxidative metabolism of flunarizine [1-[bis(4-fluorophenyl)-methyl]-4-(3-phenyl-2-propenyl)piperazine, FZ] to 1-[bis-(4-fluorophenyl)methyl]piperazine (M-1), 1-[bis(4-fluorophenyl)methyl]-4-[3-(4'...

Poly (aryl ether ketone) s with carboxylic acid groups: synthesis, sulfonation and crosslinking. Liu B, et al.

J. Mater. Chem. 18(39) , 4675-4682, (2008)

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose

Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose

Total 3, Current Page 1 of 1

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

p,p'-Difluorobenzophenone

Di-p-fluorophenyl ketone

4,4‘-Difluorobenzophenone

Bis(4-fluorophenyl)methanone

EINECS 206-466-3

4-fluorophenyl ketone

Bis(4-Fluorophenyl)-Methanone

4.4'-difluorobenzophenone

4,4'-Difluorobenzophenone

p-Fluorophenyl ketone

4,4′-difluorobenzophenone

di(4-fluorophenyl)methanone

MFCD00000353

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the InChIKey of bis(4-fluorophenyl)methanone?

A: InChIKey of bis(4-fluorophenyl)methanone is LSQARZALBDFYQZ-UHFFFAOYSA-N.

Q: What is the English name of bis(4-fluorophenyl)methanone?

A: The English name of bis(4-fluorophenyl)methanone is bis(4-fluorophenyl)methanone.

Q: What is the molecular weight of bis(4-fluorophenyl)methanone?

A: Molecular weight of bis(4-fluorophenyl)methanone is 218.199.

Q: What is the safety information for bis(4-fluorophenyl)methanone?

A: Safety information for bis(4-fluorophenyl)methanone: S26-S37/39.

Q: What is the CAS number of bis(4-fluorophenyl)methanone?

A: CAS number of bis(4-fluorophenyl)methanone is 345-92-6.

Q: What are the downstream products of bis(4-fluorophenyl)methanone?

A: Related downstream products(CAS) of bis(4-fluorophenyl)methanone: 457-68-1;456-22-4;379-57-7;16574-54-2;90-94-8;198889-20-2;365-24-2;90-96-0;345-89-1;345-90-4.

Q: What is the melting point of bis(4-fluorophenyl)methanone?

A: Melting point of bis(4-fluorophenyl)methanone is 102-105 °C(lit.).

Q: What is the polar surface area (PSA) of bis(4-fluorophenyl)methanone?

A: Polar surface area (PSA) of bis(4-fluorophenyl)methanone is 17.07000.

Q: What is the boiling point of bis(4-fluorophenyl)methanone?

A: Boiling point of bis(4-fluorophenyl)methanone is 308.8±27.0 °C at 760 mmHg.

Q: What is the molecular formula of bis(4-fluorophenyl)methanone?

A: Molecular formula of bis(4-fluorophenyl)methanone is C13H8F2O.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4,4′-difluorobenzophenone
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4,4'-Difluorobenzophenone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Bis(4-fluorophenyl)methanone
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 4,4′-difluorobenzophenone
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

Get all suppliers and price by the below link:

4,4′-difluorobenzophenone suppliers

4,4′-difluorobenzophenone price

4,4′-difluorobenzophenone

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles2

4,4′-difluorobenzophenoneBioassay

Synonyms

4,4′-difluorobenzophenone | FAQ

4,4′-difluorobenzophenonefactory

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.