Incensole acetate

Modify Date: 2024-01-09 16:59:32

Incensole acetate Structure
Incensole acetate structure
Common Name Incensole acetate
CAS Number 34701-53-6 Molecular Weight 348.519
Density 1.0±0.1 g/cm3 Boiling Point 420.1±45.0 °C at 760 mmHg
Molecular Formula C22H36O3 Melting Point N/A
MSDS N/A Flash Point 178.6±23.3 °C

 Use of Incensole acetate


Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs[1].

 Names

Name Incensole acetate
Synonym More Synonyms

 Incensole acetate Biological Activity

Description Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs[1].
Related Catalog
In Vitro Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25–35-induced cell death, a 48–52% decrease in cell viability at Aβ25–35 is restored to 85–89% upon pre-treatment with IA[1]. Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25–35 in hOBNSCs[1]. Cell Viability Assay[1] Cell Line: Human olfactory bulb neural stem cells Concentration: 100 μM Incubation Time: Pre-treatment 4 hours Result: Increased hOBNSCs cell viability induced by Aβ 25-35.
References

[1]. El-Magd MA, et al. Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells. Biomed Pharmacother. 2018 Sep;105:813-823.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 420.1±45.0 °C at 760 mmHg
Molecular Formula C22H36O3
Molecular Weight 348.519
Flash Point 178.6±23.3 °C
Exact Mass 348.266449
PSA 35.53000
LogP 6.83
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.499
Storage condition -20℃

 Synonyms

15-Oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol, 1,5,9-trimethyl-12-(1-methylethyl)-, acetate, (5Z,9Z)-
(5Z,9Z)-12-Isopropyl-1,5,9-trimethyl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-yl acetate
rel-(1R,2S,5E,9E,12S)-12-isopropyl-1,5,9-trimethyl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-yl acetate
(1R,2S,5E,9E,12S)-rel-1,5,9-Trimethyl-12-(1-methylethyl)-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol 2-acetate