LHRH (free acid) trifluoroacetate salt

Modify Date: 2024-01-06 13:16:33

LHRH (free acid) trifluoroacetate salt Structure
LHRH (free acid) trifluoroacetate salt structure
Common Name LHRH (free acid) trifluoroacetate salt
CAS Number 35263-73-1 Molecular Weight 1183.27
Density 1.54 g/cm3 Boiling Point N/A
Molecular Formula C55H74N16O14 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Danger

 Use of LHRH (free acid) trifluoroacetate salt


LHRH, the luteinizing hormone-releasing hormone, is a neuropeptide hypothalamic. LHRH regulates reproduction. LHRH can be used for the research of cancer[1].

 Names

Name lhrh
Synonym More Synonyms

 LHRH (free acid) trifluoroacetate salt Biological Activity

Description LHRH, the luteinizing hormone-releasing hormone, is a neuropeptide hypothalamic. LHRH regulates reproduction. LHRH can be used for the research of cancer[1].
Related Catalog
References

[1]. Schally AV, et, al. Discovery of LHRH and development of LHRH analogs for prostate cancer treatment. Prostate. 2017 Jun;77(9):1036-1054.  

[2]. Pearce TR, et, al. Peptide targeted lipid nanoparticles for anticancer drug delivery. Adv Mater. 2012 Jul 24;24(28):3803-22, 3710.  

 Chemical & Physical Properties

Density 1.54 g/cm3
Molecular Formula C55H74N16O14
Molecular Weight 1183.27
Exact Mass 1182.56000
PSA 466.34000
LogP 1.00640
Index of Refraction 1.709

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H360
Precautionary Statements P201-P308 + P313
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T: Toxic;
Risk Phrases R60
Safety Phrases 53-22-36/37/39-45
RIDADR NONH for all modes of transport

 Articles193

More Articles
Direct regulation of gonadotrophin-releasing hormone (GnRH) transcription by RF-amide-related peptide-3 and kisspeptin in a novel GnRH-secreting cell line, mHypoA-GnRH/GFP.

J. Neuroendocrinol. 26(12) , 888-97, (2014)

RF-amide-related peptide-3 [RFRP-3; also often referred to as the mammalian orthologue of the avian gonadotrophin-inhibitory hormone (GnIH)] and kisspeptin have emerged as potent modulators of neuroen...

Histidine(7.36(305)) in the conserved peptide receptor activation domain of the gonadotropin releasing hormone receptor couples peptide binding and receptor activation.

Mol. Cell. Endocrinol. 402 , 95-106, (2015)

Transmembrane helix seven residues of G protein-coupled receptors (GPCRs) couple agonist binding to a conserved receptor activation mechanism. Amino-terminal residues of the GnRH peptide determine ago...

Live birth rates after combined adjuvant therapy in IVF-ICSI cycles: a matched case-control study.

Reprod. Biomed. Online 30(4) , 340-8, (2015)

The effectiveness of combined co-treatment with aspirin, doxycycline, prednisolone, with or without oestradiol patches, was investigated on live birth (LBR) rates after fresh and frozen embryo transfe...

 Synonyms

PYR-HWSYGLRPG
GONADOTROPIN-RELEASING HORMONE
PYR-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY
LUTEINIZING HORMONE-RELEASING HORMONE
mammalian GnRH I
luteinizing hormone releasing hormone free acid
pEHWSYGLRPG
<Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-OH >
GLP-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY
pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-OH