SARS-CoV-2 3CLpro-IN-16

Modify Date: 2024-01-09 14:51:54

SARS-CoV-2 3CLpro-IN-16 Structure
SARS-CoV-2 3CLpro-IN-16 structure
Common Name SARS-CoV-2 3CLpro-IN-16
CAS Number 352659-40-6 Molecular Weight 294.37
Density N/A Boiling Point N/A
Molecular Formula C17H14N2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2 3CLpro-IN-16


SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 2.124 μM). SARS-CoV-2 3CLpro-IN-16 binds to the active site and forms a covalent bond with Cys145 of 3CLpro[1].

 Names

Name SARS-CoV-2 3CLpro-IN-16

 SARS-CoV-2 3CLpro-IN-16 Biological Activity

Description SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 2.124 μM). SARS-CoV-2 3CLpro-IN-16 binds to the active site and forms a covalent bond with Cys145 of 3CLpro[1].
Related Catalog
Target

2.124 μM (SARS-CoV-2 3CLpro)[1]

References

[1]. Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.  

 Chemical & Physical Properties

Molecular Formula C17H14N2OS
Molecular Weight 294.37
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