CID1231538

Modify Date: 2025-08-26 22:11:36

CID1231538 Structure
CID1231538 structure
Common Name CID1231538
CAS Number 354126-20-8 Molecular Weight 524.05
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C26H22ClN3O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CID1231538


CID1231538, a benzothiazole analogue, is a potent GPR35 antagonist (IC50=0.55 μM). GPR35 is a G protein-coupled receptor (GPCR)[1].

 Names

Name N-{2-[(4-Chlorobenzyl)sulfanyl]-1,3-benzothiazol-6-yl}-2-(4-morpholinylcarbonyl)benzamide
Synonym More Synonyms

 CID1231538 Biological Activity

Description CID1231538, a benzothiazole analogue, is a potent GPR35 antagonist (IC50=0.55 μM). GPR35 is a G protein-coupled receptor (GPCR)[1].
Related Catalog
In Vitro GPR35 has gained special consideration as a result of its association with many diseases including type-2 diabetes, nociceptive pain, inflammation, mild mental retardation syndrome, metabolic disorders, and gastric cancer[1].
References

[1]. Abdalhameed MM, et al. Structure-activity relationships of benzothiazole GPR35 antagonists. Bioorg Med Chem Lett. 2017;27(3):612-615.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C26H22ClN3O3S2
Molecular Weight 524.05
Exact Mass 523.079102
LogP 3.00
Index of Refraction 1.725

 Synonyms

N-{2-[(4-Chlorobenzyl)sulfanyl]-1,3-benzothiazol-6-yl}-2-(4-morpholinylcarbonyl)benzamide
Benzamide, N-[2-[[(4-chlorophenyl)methyl]thio]-6-benzothiazolyl]-2-(4-morpholinylcarbonyl)-
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