5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL

Modify Date: 2024-01-10 00:49:34

5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL structure	Common Name	5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL
	CAS Number	35482-50-9	Molecular Weight	258.355
	Density	1.1±0.1 g/cm3	Boiling Point	414.3±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	192.3±23.3 °C

Use of 5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL

Cannabidiorcol (CBDO, CBD-C1, O-1821) is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors (CBs) and is an agonist of the transient receptor potential channel (TRP channel), through which it produces antiinflammatory effects, but can also promote tumorigenesis at high concentrations[1][2].

Name	5-methyl-2-[(6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]benzene-1,3-diol
Synonym	More Synonyms

Description	Cannabidiorcol (CBDO, CBD-C1, O-1821) is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors (CBs) and is an agonist of the transient receptor potential channel (TRP channel), through which it produces antiinflammatory effects, but can also promote tumorigenesis at high concentrations[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	AChE:4.61 mM (Ki)
References	[1]. Teresina Laragione, et al. Combination therapy of a TRPV2 agonist with a TNF inhibitor achieves sustained suppression of disease severity and reduced joint damage. Clin Exp Immunol. 2023 Mar; 211(3): 233–238. [2]. Rongqi Huang, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma. Br J Cancer. 2022 Nov 1; 127(8): 1424–1439.

Density	1.1±0.1 g/cm3
Boiling Point	414.3±45.0 °C at 760 mmHg
Molecular Formula	C₁₇H₂₂O₂
Molecular Weight	258.355
Flash Point	192.3±23.3 °C
Exact Mass	258.161987
PSA	40.46000
LogP	4.91
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.565

Orcinol

CAS#:504-15-4

cis-Isolimonenol

CAS#:22972-51-6

~33%

5-METHYL-2-[(1R...

CAS#:35482-50-9

Literature: Baek, Seung-Hwa; Srebnik, Morris; Mechoulam, Raphael Tetrahedron Letters, 1985 , vol. 26, # 8 p. 1083 - 1086

Precursor 2
CAS#:504-15-4 Orcinol CAS#:22972-51-6 cis-Isolimonenol
DownStream 0

Cannabidiorcol

Cannabidiorocol

1,3-Benzenediol, 5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-

2-[(1R,6R)-6-Isopropenyl-3-methyl-2-cyclohexen-1-yl]-5-methyl-1,3-benzenediol

O 1821

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: ￥2000/1mg (38.70 mM * 100 μL in Acetonitrile)

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5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL

Use of 5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL

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