5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL

Modify Date: 2025-08-21 19:51:29

5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL structure	Common Name	5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL
	CAS Number	35482-50-9	Molecular Weight	258.355
	Density	1.1±0.1 g/cm3	Boiling Point	414.3±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	192.3±23.3 °C

Use of 5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL

Cannabidiorcol (CBDO, CBD-C1, O-1821) is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors (CBs) and is an agonist of the transient receptor potential channel (TRP channel), through which it produces antiinflammatory effects, but can also promote tumorigenesis at high concentrations[1][2].

Name	5-methyl-2-[(6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]benzene-1,3-diol
Synonym	More Synonyms

Description	Cannabidiorcol (CBDO, CBD-C1, O-1821) is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors (CBs) and is an agonist of the transient receptor potential channel (TRP channel), through which it produces antiinflammatory effects, but can also promote tumorigenesis at high concentrations[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	AChE:4.61 mM (Ki)
References	[1]. Teresina Laragione, et al. Combination therapy of a TRPV2 agonist with a TNF inhibitor achieves sustained suppression of disease severity and reduced joint damage. Clin Exp Immunol. 2023 Mar; 211(3): 233–238. [2]. Rongqi Huang, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma. Br J Cancer. 2022 Nov 1; 127(8): 1424–1439.

Density	1.1±0.1 g/cm3
Boiling Point	414.3±45.0 °C at 760 mmHg
Molecular Formula	C₁₇H₂₂O₂
Molecular Weight	258.355
Flash Point	192.3±23.3 °C
Exact Mass	258.161987
PSA	40.46000
LogP	4.91
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.565
InChIKey	GKVOVXWEBSQJPA-UONOGXRCSA-N
SMILES	C=C(C)C1CCC(C)=CC1c1c(O)cc(C)cc1O

Orcinol

CAS#:504-15-4

cis-Isolimonenol

CAS#:22972-51-6

~33%

5-METHYL-2-[(1R...

CAS#:35482-50-9

Literature: Baek, Seung-Hwa; Srebnik, Morris; Mechoulam, Raphael Tetrahedron Letters, 1985 , vol. 26, # 8 p. 1083 - 1086

Precursor 2
CAS#:504-15-4 Orcinol CAS#:22972-51-6 cis-Isolimonenol
DownStream 0

Name: Agonist activity at human CB2 receptor expressed in CHO cells assessed as forskolin-s...
Source: ChEMBL
Target: Cannabinoid receptor 2
External Id: CHEMBL5529047

Name: Antagonist activity at human CB1 receptor expressed in CHO cells assessed as inhibiti...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL5529046

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262

Name: Antagonist activity at human CB1 receptor expressed in CHO cells assessed as inhibiti...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL5529045

Name: A screen for small molecules that modulate mitochondrial supercomplex formation
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1482

Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN

Name: Stabilization of p53 in human papillomavirus-positive cells
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Cellular tumor antigen p53
External Id: HMS1485

Total 8, Current Page 1 of 1

Cannabidiorcol

Cannabidiorocol

2-[(1R,6R)-6-Isopropenyl-3-methyl-2-cyclohexen-1-yl]-5-methyl-1,3-benzenediol

O 1821

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: O-1821
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL suppliers

Price: ￥2000/1mg (38.70 mM * 100 μL in Acetonitrile)

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5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL

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