O-glycosylation-IN-1

Modify Date: 2024-01-24 19:32:59

O-glycosylation-IN-1 Structure
O-glycosylation-IN-1 structure
Common Name O-glycosylation-IN-1
CAS Number 3554-93-6 Molecular Weight 311.33000
Density 1.34g/cm3 Boiling Point 594.9ºC at 760mmHg
Molecular Formula C15H21NO6 Melting Point 201-203°C
MSDS USA Flash Point 313.6ºC

 Use of O-glycosylation-IN-1


O-glycosylation-IN-1 is a potent O-glycosylation inhibitor and is used to reduce mucin on cell surfaces. O-glycosylation-IN-1 inhibits the synthesis of mucin O-glycosylation of cellular models of human pancreatic cancer[1].

 Names

Name BENZYL-2-ACETAMIDO-2-DEOXY-α-D-GALACTOPYRANOSIDE
Synonym More Synonyms

 O-glycosylation-IN-1 Biological Activity

Description O-glycosylation-IN-1 is a potent O-glycosylation inhibitor and is used to reduce mucin on cell surfaces. O-glycosylation-IN-1 inhibits the synthesis of mucin O-glycosylation of cellular models of human pancreatic cancer[1].
Related Catalog
Target

O-glycosylation[1]

References

[1]. Kalra AV, et al. Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. Br J Cancer. 2007 Oct 8;97(7):910-8. Epub 2007 Oct 2.

 Chemical & Physical Properties

Density 1.34g/cm3
Boiling Point 594.9ºC at 760mmHg
Melting Point 201-203°C
Molecular Formula C15H21NO6
Molecular Weight 311.33000
Flash Point 313.6ºC
Exact Mass 311.13700
PSA 108.25000
Index of Refraction 1.59
Storage condition −20°C
Water Solubility methanol: soluble10mg/mL, clear

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
RIDADR NONH for all modes of transport
WGK Germany 3

 Precursor & DownStream

Precursor  0

DownStream  2

 Articles31

More Articles
Inhibition of CD44 N- and O-linked glycosylation decreases endometrial cell lines attachment to peritoneal mesothelial cells.

Fertil. Steril. 95(2) , 823-5, (2011)

The attachment of endometrial epithelial cells (EECs) and endometrial stromal cells (ESCs) to peritoneal mesothelial cells (PMCs) with and without inhibition of N- and O-linked glycosylation, the viab...

Antiadhesive character of mucin O-glycans at the apical surface of corneal epithelial cells.

Invest. Ophthalmol. Vis. Sci. 49(1) , 197-203, (2008)

Prolonged contact of opposite mucosal surfaces, which occurs on the ocular surface, oral cavity, reproductive tract, and gut, requires a specialized apical cell surface that prevents adhesion. The pur...

Benzyl-N-acetyl-alpha-D-galactosaminide induces a storage disease-like phenotype by perturbing the endocytic pathway.

J. Biol. Chem. 278(14) , 12374-83, (2003)

The sugar analog O-benzyl-N-acetyl-alpha-d-galactosaminide (BG) is an inhibitor of glycan chain elongation and inhibits alpha2,3-sialylation in mucus-secreting HT-29 cells. Long-term exposure of these...

 Synonyms

MFCD00057920
16beta-Hydroxydisitoxigenin
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