5-Nitroso-8-quinolinol

Modify Date: 2026-06-29 19:20:38

5-Nitroso-8-quinolinol Structure
5-Nitroso-8-quinolinol structure
Common Name 5-Nitroso-8-quinolinol
CAS Number 3565-26-2 Molecular Weight 174.156
Density 1.4±0.1 g/cm3 Boiling Point 403.3±30.0 °C at 760 mmHg
Molecular Formula C9H6N2O2 Melting Point 245 °C
MSDS N/A Flash Point 197.7±24.6 °C

 Names

Name 5-nitrosoquinolin-8-ol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 403.3±30.0 °C at 760 mmHg
Melting Point 245 °C
Molecular Formula C9H6N2O2
Molecular Weight 174.156
Flash Point 197.7±24.6 °C
Exact Mass 174.042923
PSA 62.55000
LogP 1.66
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.675
InChIKey RZWRYPGAUIOOMK-UHFFFAOYSA-N
SMILES O=Nc1ccc(O)c2ncccc12
Storage condition Store at RT

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC8237000
CHEMICAL NAME :
8-Quinolinol, 5-nitroso-
CAS REGISTRY NUMBER :
3565-26-2
BEILSTEIN REFERENCE NO. :
0135353
LAST UPDATED :
199712
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H6-N2-O2
MOLECULAR WEIGHT :
174.17
WISWESSER LINE NOTATION :
T66 BNJ GNO JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
296 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
1 umol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 164,263,1986

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases R5
Safety Phrases S36/37
RIDADR 3224.0
Hazard Class 4.1
HS Code 2933499090

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 5-Nitroso-8-quinolinolBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: CHOP dose-response primary assay
Source: Emory University Molecular Libraries Screening Center
Target: DNA damage-inducible transcript 3 protein [Mus musculus]
External Id: CHOP dose-response primary assay
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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 Synonyms

Hydron III
5-Nitroso-8-cinnolinol
5-nitrosoquinolin-8-ol
8-QUINOLINOL,5-NITROSO
5-Nitroso-oxine
5-Nitroso-8-quinolinol
8-Hydroxy-5-nitrosoquinoline
EINECS 222-650-6
5-Nitroso-chinolin-8-ol
5-NITROSO-8-HYDROXYQUINOLINE
5-Nitrosooxine
5-Nitroso-8-hydroxy-chinolin
MFCD00041862
5-nitroso-quinolin-8-ol
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