N-methyl-L-glutamic acid

Modify Date: 2025-08-25 13:18:00

N-methyl-L-glutamic acid Structure
N-methyl-L-glutamic acid structure
 Common Name N-methyl-L-glutamic acid
CAS Number 35989-16-3 Molecular Weight 197.617
Density 1.278g/cm3 Boiling Point 330.2ºC at 760mmHg
Molecular Formula C6H12ClNO4 Melting Point N/A
MSDS USA Flash Point 153.5ºC

 Use of N-methyl-L-glutamic acid


N-Methyl-DL-glutamic acid is a L-Glutamic acid (HY-14608) analog with cytotoxic effects[1][2].

 Names

Name N-methyl-L-glutamic acid
Synonym More Synonyms

 N-methyl-L-glutamic acid Biological Activity

Description N-Methyl-DL-glutamic acid is a L-Glutamic acid (HY-14608) analog with cytotoxic effects[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Olney JW, et al. Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system. Exp Brain Res. 1971;14(1):61-76.

[2]. Chan PH, et al. Effects of excitatory neurotransmitter amino acids on swelling of rat brain cortical slices. J Neurochem. 1979 Dec;33(6):1309-15.

 Chemical & Physical Properties

Density 1.278g/cm3
Boiling Point 330.2ºC at 760mmHg
Molecular Formula C6H12ClNO4
Molecular Weight 197.617
Flash Point 153.5ºC
Exact Mass 197.045486
PSA 86.63000
Index of Refraction 1.491
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
HS Code 2922499990

 Synthetic Route

N-benzyloxycarbonyl-N-methyl-DL-glutamic acid structure

N-benzyloxycarb...

CAS#:56618-13-4

~61%

N-methyl-L-glutamic acid Structure

N-methyl-L-glut...

CAS#:35989-16-3

Literature: Hughes, Andrew B.; Mackay, Maureen F.; Aurelio, Luigi Australian Journal of Chemistry, 2000 , vol. 53, # 3 p. 237 - 240 Title/Abstract Full Text View citing articles Show Details Aurelio, Luigi; Brownlee, Robert T. C.; Hughes, Andrew B.; Sleebs, Brad E. Australian Journal of Chemistry, 2000 , vol. 53, # 5 p. 425 - 433
3-(2-oxo-3-phenylmethoxycarbonyl-1,3-oxazolidin-4-yl)propanoic acid structure

3-(2-oxo-3-phen...

CAS#:19525-56-5

~%

N-methyl-L-glutamic acid Structure

N-methyl-L-glut...

CAS#:35989-16-3

Literature: Australian Journal of Chemistry, , vol. 53, # 3 p. 237 - 240
Z-Glu-OH structure

Z-Glu-OH

CAS#:1155-62-0

~%

N-methyl-L-glutamic acid Structure

N-methyl-L-glut...

CAS#:35989-16-3

Literature: Australian Journal of Chemistry, , vol. 53, # 5 p. 425 - 433
2-Ketoglutaric acid structure

2-Ketoglutaric acid

CAS#:328-50-7

methylamine structure

methylamine

CAS#:74-89-5

~%

N-methyl-L-glutamic acid Structure

N-methyl-L-glut...

CAS#:35989-16-3

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 148, p. 311 Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 170, p. 187,195
POTASSIUM CYANIDE structure

POTASSIUM CYANIDE

CAS#:151-50-8

methylamine structure

methylamine

CAS#:74-89-5

~%

N-methyl-L-glutamic acid Structure

N-methyl-L-glut...

CAS#:35989-16-3

Literature: Yakugaku Zasshi, , p. 150 Chem. Zentralbl., , vol. 99, # I p. 1643

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles1

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 Synonyms

N-Methyl-DL-glutamic Acid
MFCD00037760
Glutamic acid, N-methyl-, hydrochloride (1:1)
N-Methylglutamic acid hydrochloride (1:1)
2-(Methylamino)pentanedioic acid
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