3'-Deoxyguanosine
3'-Deoxyguanosine structure
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Common Name | 3'-Deoxyguanosine | ||
|---|---|---|---|---|
| CAS Number | 3608-58-0 | Molecular Weight | 267.24 | |
| Density | 2.1±0.1 g/cm3 | Boiling Point | 725.5±70.0 °C at 760 mmHg | |
| Molecular Formula | C10H13N5O4 | Melting Point | <300℃ (water ) | |
| MSDS | USA | Flash Point | 392.6±35.7 °C | |
Use of 3'-Deoxyguanosine3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 3'-deoxyguanosine |
|---|---|
| Synonym | More Synonyms |
| Description | 3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 725.5±70.0 °C at 760 mmHg |
| Melting Point | <300℃ (water ) |
| Molecular Formula | C10H13N5O4 |
| Molecular Weight | 267.24 |
| Flash Point | 392.6±35.7 °C |
| Exact Mass | 267.096741 |
| PSA | 140.01000 |
| LogP | -0.72 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.907 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2934999090 |
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~99%
3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Bhan, Purshotam; Bhan, Anila; Hong, Mikung; Hartwell, John G.; Saunders, June M.; Hoke, GlennD Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1195 - 1199 |
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3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 |
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3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 |
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3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 |
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3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 22, # 5-8 p. 751 - 753 |
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~%
3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 22, # 5-8 p. 751 - 753 |
|
~%
3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Nucleosides and Nucleotides, , vol. 16, # 7-9 p. 1195 - 1199 |
|
~%
3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Nucleosides and Nucleotides, , vol. 16, # 7-9 p. 1195 - 1199 |
|
~%
3'-Deoxyguanosine CAS#:3608-58-0 |
| Literature: Nucleosides and Nucleotides, , vol. 13, # 5 p. 1049 - 1058 |
![N2-[(dimethylamino)methylene]guanosine structure](https://image.chemsrc.com/caspic/442/1055407-32-3.png)
| Precursor 9 | |
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| DownStream 2 | |
![N-[9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide structure](https://image.chemsrc.com/caspic/050/157025-66-6.png)
CAS#:157025-66-6
CAS#:869355-04-4| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Rat brain guanosine binding site. Biological studies and pseudo-receptor construction.
Bioorg. Med. Chem. 11 , 5417-5425, (2003) Rat brain guanosine binding sites were studied by (i). a pharmacological approach to confirm the hypothesis of the existence of specific G-coupled receptors for guanosine (1) and, for the first time, ... |
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Structure of human PNP complexed with ligands.
Acta Crystallogr. D Biol. Crystallogr. 61 , 856-862, (2005) Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine-salvage pathway, which allows cells to utilize preformed bases and nucleosides in order to synthesize nucleotides. PNP is specific f... |
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Effects of polyadenylation inhibition on meiosis progression in relation to the polyadenylation status of cyclins A2 and B1 during in vitro maturation of bovine oocytes.
Mol. Reprod. Dev. 71 , 107-114, (2005) The control of protein synthesis during maturation in oocytes is mainly exerted through cytoplasmic polyadenylation of stored mRNAs. We first analyzed the polyadenylation status of cyclins A2 and B1 d... |
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Name: Inhibitory concentration against hepatitis C virus NS5B-mediated RNA synthesis in HBI...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL824929
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Name: Inhibition HCV RNA replication
Source: ChEMBL
Target: RNA-directed RNA polymerase
External Id: CHEMBL691888
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Name: Inhibition HCV NS5B-mediated RNA synthesis
Source: ChEMBL
Target: RNA-directed RNA polymerase
External Id: CHEMBL691889
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Name: Inhibition of Hepatitis C virus NS5B RNA-dependent RNA polymerase
Source: ChEMBL
Target: N/A
External Id: CHEMBL2025703
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Name: Effective concentration against hepatitis C virus RNA replication in a subgenomic bic...
Source: ChEMBL
Target: N/A
External Id: CHEMBL834418
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| 3'-Deoxy-D-guanosine |
| MFCD00079149 |
| 3'-deoxyriboguanosine |
| 3'-Deoxyguanosine |
| 3'-deoxyguanosine monohydrate |
| 2-amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-ol |
| 3'-deoxy-guanosine |
| 3'-DG |