3'-Deoxyguanosine
3'-Deoxyguanosine structure
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Common Name | 3'-Deoxyguanosine | ||
|---|---|---|---|---|
| CAS Number | 3608-58-0 | Molecular Weight | 267.24 | |
| Density | 2.1±0.1 g/cm3 | Boiling Point | 725.5±70.0 °C at 760 mmHg | |
| Molecular Formula | C10H13N5O4 | Melting Point | <300℃ (water ) | |
| MSDS | USA | Flash Point | 392.6±35.7 °C | |
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Rat brain guanosine binding site. Biological studies and pseudo-receptor construction.
Bioorg. Med. Chem. 11 , 5417-5425, (2003) Rat brain guanosine binding sites were studied by (i). a pharmacological approach to confirm the hypothesis of the existence of specific G-coupled receptors for guanosine (1) and, for the first time, delineate a structure-activity relationship for a series of... |
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Structure of human PNP complexed with ligands.
Acta Crystallogr. D Biol. Crystallogr. 61 , 856-862, (2005) Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine-salvage pathway, which allows cells to utilize preformed bases and nucleosides in order to synthesize nucleotides. PNP is specific for purine nucleosides in the beta-configuration and exhibit... |
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Effects of polyadenylation inhibition on meiosis progression in relation to the polyadenylation status of cyclins A2 and B1 during in vitro maturation of bovine oocytes.
Mol. Reprod. Dev. 71 , 107-114, (2005) The control of protein synthesis during maturation in oocytes is mainly exerted through cytoplasmic polyadenylation of stored mRNAs. We first analyzed the polyadenylation status of cyclins A2 and B1 during in vitro maturation (IVM) of bovine oocytes, using Ra... |
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Inhibition of the replication of a hepatitis C virus-like RNA template by interferon and 3'-deoxycytidine.
Antivir. Chem. Chemother. 13(6) , 363-70, (2002) The development of low molecular weight inhibitors of hepatitis C virus (HCV) replication has been hindered by the lack of a good cell-based system that models the entire HCV replication cycle. To date the only two therapies approved for the treatment of HCV ... |