5-Bromo-2,4-dichloropyrimidine

Modify Date: 2024-01-01 17:41:39

5-Bromo-2,4-dichloropyrimidine Structure
5-Bromo-2,4-dichloropyrimidine structure
Common Name 5-Bromo-2,4-dichloropyrimidine
CAS Number 36082-50-5 Molecular Weight 227.874
Density 2.0±0.1 g/cm3 Boiling Point 287.5±20.0 °C at 760 mmHg
Molecular Formula C4HBrCl2N2 Melting Point 29-30 °C(lit.)
MSDS Chinese USA Flash Point 127.7±21.8 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Names

Name 5-Bromo-2,4-dichloropyrimidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 287.5±20.0 °C at 760 mmHg
Melting Point 29-30 °C(lit.)
Molecular Formula C4HBrCl2N2
Molecular Weight 227.874
Flash Point 127.7±21.8 °C
Exact Mass 225.870010
PSA 25.78000
LogP 2.06
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.605
Storage condition Keep Cold

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H301 + H311 + H331-H314-H317
Precautionary Statements P261-P280-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges
Hazard Codes T:Toxic
Risk Phrases R23/24/25;R34
Safety Phrases S26-S27-S36/37/39-S45
RIDADR UN 3263 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2933599090

 Synthetic Route

~81%

5-Bromo-2,4-dichloropyrimidine Structure

5-Bromo-2,4-dic...

CAS#:36082-50-5

Literature: PCR, Incorporated Patent: US4299961 A1, 1981 ;

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5-Bromo-2,4-dichloropyrimidine Structure

5-Bromo-2,4-dic...

CAS#:36082-50-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7169 - 7173,5

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5-Bromo-2,4-dichloropyrimidine Structure

5-Bromo-2,4-dic...

CAS#:36082-50-5

Literature: American Chemical Journal, , vol. 33, p. 443

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles6

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Abnormal activation or overexpression of Mer receptor tyrosine kinase has been implicated in survival signaling and chemoresistance in many human cancers. Consequently, Mer is a promising novel cancer...

Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.

Bioorg. Med. Chem. Lett. 17(22) , 6206-11, (2007)

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Synthesis , 861, (2006)

 Synonyms

5-bromo-2,4-dichloropyrimdine
Pyrimidine, 5-bromo-2,4-dichloro-
5-Brom-2,4-dichlor-pyrimidin
5-Bromo-2,4-dichloropyrimidine
MFCD00127818
2,4,4-TRIMETHYLCYCLOPENTANONE
5-Bromo-2,4-dichloro-pyrimidine
2,4-Dichloro-5-bromo pyrimidine
5-Bromo-2,4-dichloror-pyrimidine
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