G3335
G3335 structure
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Common Name | G3335 | ||
|---|---|---|---|---|
| CAS Number | 36099-95-3 | Molecular Weight | 333.33900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H19N3O5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of G3335H-Trp-Glu-OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-Trp-Glu-OH might be developed as a possible lead compound in diabetes research[1]. |
Summary: H-TRP-GLU-OH (G3335), with the chemical name 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid, is a white to off-white powder, CAS number 36099-95-3, molecular formula C16H19N3O5, and molecular weight 333.33900. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | H-Trp-Glu-OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-Trp-Glu-OH might be developed as a possible lead compound in diabetes research[1]. |
|---|---|
| Related Catalog | |
| Target |
PPARγ:8 μM (Kd) |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C16H19N3O5 |
|---|---|
| Molecular Weight | 333.33900 |
| Exact Mass | 333.13200 |
| PSA | 145.51000 |
| LogP | 1.56310 |
| InChIKey | PWIQCLSQVQBOQV-AAEUAGOBSA-N |
| SMILES | NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(=O)O)C(=O)O |
| Storage condition | -20℃ |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| RIDADR | NONH for all modes of transport |
|---|---|
| HS Code | 2933990090 |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as increase of...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3292019
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as increase of...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3292018
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as increase of...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3292021
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as increase of...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3292020
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as increase of...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3292023
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as increase of...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3292022
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Name: Percent inhibition of Dipeptidyl peptidase IV (DPP IV) at a concentration of 10 uM
Source: ChEMBL
Target: Dipeptidyl peptidase 4
External Id: CHEMBL857575
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as induction o...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3292024
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as reduction o...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3291743
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Name: Agonist activity at PPARalpha in lipid loaded rat HII4E cells assessed as reduction o...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor alpha
External Id: CHEMBL3291742
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| PPARgamma Antagonist III,G3335 |
| IN1159 |
| TRP-GLU |
| tryptophylglutamic acid |
| L-tryptophyl-L-glutamic acid |
| H-Trp-Glu-OH |
| PPARg Antagonist III,G3335 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: LogP of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid is 1.56310. |
| Q: What is the InChIKey of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: InChIKey of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid is PWIQCLSQVQBOQV-AAEUAGOBSA-N. |
| Q: What is the molecular weight of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: Molecular weight of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid is 333.33900. |
| Q: What English synonyms does 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid have? |
| A: English synonyms of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid: PPARgamma Antagonist III,G3335, IN1159, TRP-GLU, tryptophylglutamic acid, L-tryptophyl-L-glutamic acid, H-Trp-Glu-OH, PPARg Antagonist III,G3335. |
| Q: What is the English name of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: The English name of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid is 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid. |
| Q: What are the storage conditions for 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: Storage conditions for 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid: -20℃. |
| Q: What is the SMILES notation of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: SMILES notation of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid is NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(=O)O)C(=O)O. |
| Q: What are the uses of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: Main uses of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid: H-Trp-Glu-OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-Trp-Glu-OH might be developed as a possible lead compound in diabetes research[1]. |
| Q: What is the Chinese name of 36099-95-3? |
| A: Chinese name of 36099-95-3 is H-TRP-GLU-OH. |
| Q: What is the CAS number of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid? |
| A: CAS number of 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid is 36099-95-3. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |