4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-

Modify Date: 2025-08-25 10:43:40

4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl- structure	Common Name	4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-
	CAS Number	3637-11-4	Molecular Weight	171.23700
	Density	1.02g/cm3	Boiling Point	257.5ºC at 760mmHg
	Molecular Formula	C₉H₁₇NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	109.5ºC

Use of 4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-

Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H[1][2].

Name	1-hydroxy-2,2,6,6-tetramethylpiperidin-4-one
Synonym	More Synonyms

Description	Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	Using TEMPONE-H the obtained sensitivity in the detection of peroxynitrite or superoxide radicals is about 10-fold higher than using the spin traps DMPO or TMIO[1].
References	[1]. Dikalov S, et al. Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine. Biochem Biophys Res Commun. 1997 Jan 3;230(1):54-7. [2]. Dikalov SI, et al. Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. J Biol Chem. 1999 Apr 2;274(14):9392-9.

Density	1.02g/cm3
Boiling Point	257.5ºC at 760mmHg
Molecular Formula	C₉H₁₇NO₂
Molecular Weight	171.23700
Flash Point	109.5ºC
Exact Mass	171.12600
PSA	40.54000
LogP	1.53560
Storage condition	-20°C

HS Code	2933399090

Precursor 8
CAS#:826-36-8 2,2,6,6-tetrame... CAS#:7031-93-8 2,2,6,6-Tetrame... CAS#:68872-08-2 N-Piperidinocar... CAS#:7419-56-9 N-tert-butyl-N-...
CAS#:68872-05-9 N-(3-Phenylprop... CAS#:58621-80-0 N-(1,1-dimethyl... CAS#:1613-78-1 N-hydroxy-N-(1,... CAS#:68872-04-8 N-tert-Butyl-N-...
DownStream 3
CAS#:22459-57-0 2,4,6-triphenyl... CAS#:7031-85-8 1-Benzoyloxy-2,... CAS#:7031-93-8 2,2,6,6-Tetrame...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-hydroxy-2,2,6,6-tetramethyl-piperidin-4-one

1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine

4-oxo-TEMPO-H

4-Piperidinone,1-hydroxy-2,2,6,6-tetramethyl

1-Hydroxy-2,2,6,6-tetramethyl-piperidin-4-on

2,2,6,6-tetramethyl-4-oxo-1-piperidinyloxy

Tempone-H

N-hydroxy-4-oxo-2,2,6,6-tetramethylpiperidine

1-Hydroxy-2,2,6,6-tetramethyl-4-piperidinone

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4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-

Use of 4-Piperidone, 1-hydroxy-2,2,6,6-tetramethyl-

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Precursor & DownStream

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.