8-Shogaol

Modify Date: 2025-08-25 14:16:29

8-Shogaol structure	Common Name	8-Shogaol
	CAS Number	36700-45-5	Molecular Weight	304.424
	Density	1.0±0.1 g/cm3	Boiling Point	452.3±35.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₂₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	154.6±19.4 °C

Use of 8-Shogaol

[8]-Shogaol, one of the pungent phenolic compounds in ginger, exhibits anti-platelet activity (IC50=5 μM) and inhibits COX-2 (IC50=17.5 μM). [8]-Shogaol induces apoptosis in human leukemia cells[1][2][3][4].

Name	(E)-1-(4-hydroxy-3-methoxyphenyl)dodec-4-en-3-one
Synonym	More Synonyms

Description	[8]-Shogaol, one of the pungent phenolic compounds in ginger, exhibits anti-platelet activity (IC50=5 μM) and inhibits COX-2 (IC50=17.5 μM). [8]-Shogaol induces apoptosis in human leukemia cells[1][2][3][4].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2:17.5 μM (IC50)
References	[1]. Shieh PC, et al. Induction of apoptosis by [8]-shogaol via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia cells. J Agric Food Chem. 2010 Mar 24;58(6):3847-54. [2]. van Breemen RB, et al. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011 Jan;82(1):38-43. [3]. Nurtjahja-Tjendraputra E, et al. Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger. Thromb Res. 2003;111(4-5):259-65. [4]. Shieh PC, et al. Induction of apoptosis by [8]-shogaol via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia cells. J Agric Food Chem. 2010 Mar 24;58(6):3847-54.

Density	1.0±0.1 g/cm3
Boiling Point	452.3±35.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₈O₃
Molecular Weight	304.424
Flash Point	154.6±19.4 °C
Exact Mass	304.203857
PSA	46.53000
LogP	4.91
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.516
InChIKey	LGZSMXJRMTYABD-MDZDMXLPSA-N
SMILES	CCCCCCCC=CC(=O)CCc1ccc(O)c(OC)c1

4-Dodecen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, (4E)-

(4E)-1-(4-hydroxy-3-methoxyphenyl)dodec-4-en-3-one

8-Shogaol

(4E)-1-(4-Hydroxy-3-methoxyphenyl)-4-dodecen-3-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 8-Shogaol
Price: Check
Purity: 97.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 8-Shogaol
Price: ￥4418.0/20mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 8-SHOGAOL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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