Azlocillin

Modify Date: 2024-01-11 18:57:27

Azlocillin structure	Common Name	Azlocillin
	CAS Number	37091-66-0	Molecular Weight	461.491
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₃N₅O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Azlocillin

Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection[1][2].

Name	azlocillin
Synonym	More Synonyms

Description	Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Sanders CC. Azlocillin: a new broad spectrum penicillin. J Antimicrob Chemother. 1983 May;11 Suppl B:21-31. [2]. Pothineni VR, et al. Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. Sci Rep. 2020 Mar 2;10(1):3798.

Description

Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection[1][2].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Sanders CC. Azlocillin: a new broad spectrum penicillin. J Antimicrob Chemother. 1983 May;11 Suppl B:21-31.

[2]. Pothineni VR, et al. Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. Sci Rep. 2020 Mar 2;10(1):3798.

Density	1.6±0.1 g/cm3
Molecular Formula	C₂₀H₂₃N₅O₆S
Molecular Weight	461.491
Exact Mass	461.136902
PSA	173.45000
LogP	-0.34
Index of Refraction	1.697

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~89%

Azlocillin

CAS#:37091-66-0

Literature: Koenig, Hans-Bodo; Metzer, Karl-Georg; Offe, Hans-Albert; Schroeck, Wilfried European Journal of Medicinal Chemistry, 1982 , vol. 17, # 1 p. 59 - 63

6-Aminopenicill...

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Azlocillin

CAS#:37091-66-0

Literature: Koenig, Hans-Bodo; Metzer, Karl-Georg; Offe, Hans-Albert; Schroeck, Wilfried European Journal of Medicinal Chemistry, 1982 , vol. 17, # 1 p. 59 - 63

Precursor 4
CAS#:69-53-4 Ampicillin CAS#:13214-53-4 1-Chlorocarbony... CAS#:551-16-6 6-Aminopenicill... CAS#:37091-70-6 D-α-(2-Oxo-imid...
DownStream 0

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxo-1-imidazolidinyl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Azlocillin

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, (2S,5R,6R)-

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((R)-2-(2-oxo-1-imidazolidinecarboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid