Methyl tert-butyl ether

Modify Date: 2025-08-20 13:34:08

Methyl tert-butyl ether structure	Common Name	Methyl tert-butyl ether
	CAS Number	1634-04-4	Molecular Weight	88.148
	Density	0.8±0.1 g/cm3	Boiling Point	55.2±0.0 °C at 760 mmHg
	Molecular Formula	C₅H₁₂O	Melting Point	-110 °C
	MSDS	Chinese USA	Flash Point	-10.0±0.0 °C
	Symbol	GHS02, GHS07	Signal Word	Danger

Name	methyl tert-butyl ether
Synonym	More Synonyms

Density	0.8±0.1 g/cm3
Boiling Point	55.2±0.0 °C at 760 mmHg
Melting Point	-110 °C
Molecular Formula	C₅H₁₂O
Molecular Weight	88.148
Flash Point	-10.0±0.0 °C
Exact Mass	88.088814
PSA	9.23000
LogP	1.15
Vapour density	3.1 (vs air)
Vapour Pressure	251.3±0.1 mmHg at 25°C
Index of Refraction	1.375
Storage condition	−20°C
Stability	Stable, but may form explosive peroxides in contact with air. Extremely flammable - note low flash point. Incompatible with strong oxidizing agents.
Water Solubility	51 g/L (20 ºC)
Freezing Point	-108.6℃

Methyl tert-butyl ether MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KN5250000

CHEMICAL NAME :: Ether, tert-butyl methyl

CAS REGISTRY NUMBER :: 1634-04-4

BEILSTEIN REFERENCE NO. :: 1730942

LAST UPDATED :: 199712

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C5-H12-O

MOLECULAR WEIGHT :: 88.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-174603

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 23576 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-174603

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >148 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JSGRA2 Journal of Surgical Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1961- Volume(issue)/page/year: 53,572,1992

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 148 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JSGRA2 Journal of Surgical Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1961- Volume(issue)/page/year: 53,572,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5960 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHHTAT Zhonghua Yixue Zazhi. Chinese Medical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1915- Suspended 1967-72. Volume(issue)/page/year: 70,172,1990

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 141 gm/m3/15M

TOXIC EFFECTS :: Behavioral - general anesthetic

REFERENCE :: ANESAV Anesthesiology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1940- Volume(issue)/page/year: 11,455,1950

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1700 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHHTAT Zhonghua Yixue Zazhi. Chinese Medical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1915- Suspended 1967-72. Volume(issue)/page/year: 70,172,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 gm/kg/14D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(5),525,1990

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27 gm/kg/90D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - changes in calcium

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(5),525,1990

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1516 ppm/6H/10D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 143,301,1997 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 8000 ppm/6H

SEX/DURATION :: multigeneration

TOXIC EFFECTS :: Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 17(S1),S13,1997

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 4000 ppm/6H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 17(S1),S21,1997

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 8000 ppm/6H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 17(S1),S21,1997 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 144 mg/m3 (40 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 100 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4267 No. of Facilities: 614 (estimated) No. of Industries: 6 No. of Occupations: 9 No. of Employees: 5996 (estimated) No. of Female Employees: 1783 (estimated)

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H315
Precautionary Statements	P210
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes	F:Flammable
Risk Phrases	R11;R38
Safety Phrases	S9-S16-S24-S45-S36/37
RIDADR	UN 2398 3/PG 2
WGK Germany	3
RTECS	KN5250000
Packaging Group	II
Hazard Class	3
HS Code	2909199090

Precursor 10
CAS#:1642-81-5 4-(Chloromethyl... CAS#:75-65-0 tert-Butanol CAS#:74-88-4 methyl iodide CAS#:67-56-1 Methanol
CAS#:115-11-7 Isobutylene CAS#:77-78-1 Dimethyl sulfate CAS#:36171-18-3 N-tert-butyl-N-... CAS#:628-28-4 1-Methoxybutane
CAS#:99-96-7 4-Hydroxybenzoi... CAS#:107-31-3 methyl formate
DownStream 9
CAS#:10284-51-2 1-(1-butoxyethe... CAS#:354-92-7 1,1,1,2,3,3,3-h... CAS#:681-08-3 1-tert-butoxy-2... CAS#:110719-85-2 2-[difluoro(tri...
CAS#:59571-40-3 1-hydronona-flu... CAS#:106089-24-1 (R)-1-Methacryl... CAS#:35654-56-9 4-Chloro-6,7-di... CAS#:372-39-4 3,5-Difluoroaniline
CAS#:5545-52-8 Z-Asp(OtBu)-OH.H2O

HS Code	2909199090
Summary	2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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Propane, 2-methoxy-2-methyl-

methyl t-butyl ether

Methyl tert-butyl ether

ARCOPURE(R) MTBE

tert-BuOCH3

tert-butylmethyl ether

MTBE

Methyl tertiary-butyl ether

EINECS 216-653-1

MBT-ETHER

tert-butyl methyl ether

Methyl -butyl ether

Driveron

methyl-t-butyl ether

(CH3)3COCH3

BOC-L-ARG(MTR)-OH

tert-butyl-methyl-ether

TBME

tert-C4H9OCH3

2-methoxy-2-methyl

2-Methoxy-2-methylpropane

HP-MTBE

t-butyl methyl ether

MFCD00008812

Methyl 1,1-dimethylethyl ether

MTBE,Methyl tert-butyl ether

Ether, tert-butyl methyl

methyl-tert-butyl ether

MTB

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Methyl tert-butyl ether
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Methyl tert-butyl ether
Price: ￥518.0/1l ￥368.0/500ml ￥208.0/100ml ￥158.0/500ml
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: tert-Butyl methyl ether
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU-CHEM CAS:1634-04-4 tert-Butyl methyl ether
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Methyl tert-butyl ether

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