Human β-defensin-2

Modify Date: 2025-08-26 17:41:51

Human β-defensin-2 Structure
Human β-defensin-2 structure
Common Name Human β-defensin-2
CAS Number 372146-20-8 Molecular Weight 4328.20
Density N/A Boiling Point N/A
Molecular Formula C188H305N55O50S6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Human β-defensin-2


Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus[1]. Human β-defensin-2 can be used for the study of colitis[2].

 Names

Name Human β-defensin-2

 Human β-defensin-2 Biological Activity

Description Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus[1]. Human β-defensin-2 can be used for the study of colitis[2].
Related Catalog
Target

Target: bacteria[1]

References

[1]. J M Schröder, et al. Human beta-defensin-2. Int J Biochem Cell Biol

[2]. Louis Koeninger, et al. Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis. Front Immunol. 2020 Jan 31;11:93.

 Chemical & Physical Properties

Molecular Formula C188H305N55O50S6
Molecular Weight 4328.20
InChIKey JJDUNZFWULIMFT-YIYXCTSTSA-N
SMILES CCC(C)C(NC(=O)CN)C(=O)NCC(=O)NC(CC(=O)O)C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC1CSSCC2NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)CNC(=O)C3CCCN3C(=O)C(CC(C)C)NC(=O)CNC(=O)C3CSSCC(NC(=O)C(C(C)CC)NC(=O)C(C)NC(=O)CNC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC1=O)C(=O)NC(Cc1cnc[nH]1)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(CSSCC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O)NC2=O)C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(C(C)O)C(=O)N3)C(C)O)C(C)C.O=C(O)C(F)(F)F
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