4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL

Modify Date: 2024-01-04 21:58:02

4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL Structure
4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL structure
 Common Name 4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL
CAS Number 373603-69-1 Molecular Weight 169.14500
Density N/A Boiling Point 175.1±35.0 °C at 760 mmHg
Molecular Formula C6H10F3NO Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-(Trifluoromethyl)-4-piperidinol
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 175.1±35.0 °C at 760 mmHg
Molecular Formula C6H10F3NO
Molecular Weight 169.14500
Exact Mass 169.07100
PSA 32.26000
LogP 0.99200

 Safety Information

Hazard Codes Xn

 Synthetic Route

1-benzyl-4-trifluoromethyl-piperidin-4-ol structure

1-benzyl-4-trif...

CAS#:373603-70-4

~99%

4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL Structure

4-(TRIFLUOROMET...

CAS#:373603-69-1

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2005/103002 A2, 2005 ; Location in patent: Page/Page column 34 ; WO 2005/103002 A2
4-hydroxy-4-trifluoromethyl-piperidine-1-carboxylic acid benzyl ester structure

4-hydroxy-4-tri...

CAS#:946504-83-2

~97%

4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL Structure

4-(TRIFLUOROMET...

CAS#:373603-69-1

Literature: Hendricks, Robert Than; Hermann, Johannes; Kondru, Rama; Lou, Yan; Lynch, Stephen M.; Owens, Timothy D.; Soth, Michael Patent: US2011/230462 A1, 2011 ; Location in patent: Page/Page column 81 ; US 20110230462 A1
tert-butyl 4-hydroxy-4-(trifluoromethyl)piperidine-1-carboxylate structure

tert-butyl 4-hy...

CAS#:550371-74-9

~99%

4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL Structure

4-(TRIFLUOROMET...

CAS#:373603-69-1

Literature: EXELIXIS, INC.; AAY, Naing; ARCALAS, Arlyn; BOWLES, Owen, Joseph; BUSSENIUS, Joerg; CURTIS, Jeffry, Kimo; DEFINA, Steven, Charles; DUBENKO, Larisa; HARRIS, Jason, R.; JACKSON-UGUETO, Eileen, E.; MANALO, Jean-Claire, Limun; KIM, Angie, Inyoung; PACK, Michael; PETO, Csaba, J.; RICE, Kenneth, D.; TSANG, Tsze, H. Patent: WO2010/138487 A1, 2010 ; Location in patent: Page/Page column 130 ; WO 2010/138487 A1
tert-butyl 4-hydroxy-4-(trifluoromethyl)piperidine-1-carboxylate structure

tert-butyl 4-hy...

CAS#:550371-74-9

trifluoroacetic acid structure

trifluoroacetic acid

CAS#:76-05-1

~99%

4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL Structure

4-(TRIFLUOROMET...

CAS#:373603-69-1

Literature: EXELIXIS, INC.; RICE, Kenneth Patent: WO2012/71509 A2, 2012 ; Location in patent: Page/Page column 165 ; WO 2012/071509 A2
N-CBZ-4-piperidone structure

N-CBZ-4-piperidone

CAS#:19099-93-5

~%

4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL Structure

4-(TRIFLUOROMET...

CAS#:373603-69-1

Literature: Hendricks, Robert Than; Hermann, Johannes; Kondru, Rama; Lou, Yan; Lynch, Stephen M.; Owens, Timothy D.; Soth, Michael Patent: US2011/230462 A1, 2011 ; US 20110230462 A1
N-(tert-Butoxycarbonyl)-4-piperidone structure

N-(tert-Butoxyc...

CAS#:79099-07-3

~%

4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL Structure

4-(TRIFLUOROMET...

CAS#:373603-69-1

Literature: EXELIXIS, INC.; RICE, Kenneth Patent: WO2012/71509 A2, 2012 ; WO 2012/071509 A2

 Synonyms

4-trifluoromethylpiperidin-4-ol
4-hydroxy-4-tert-butoxycarbonylaminomethylpiperidine
4-hydroxy-4-trifluoromethyl-piperdine
4-hydroxy-4-trifluoromethyl-piperidine
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Related Compounds: More...
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Chemsrc provides 4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL(CAS#:373603-69-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL are included as well.>> amp version: 4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL

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