4-methylumbelliferyl α-D-galactoside

Modify Date: 2024-01-05 08:46:57

4-methylumbelliferyl α-D-galactoside Structure
4-methylumbelliferyl α-D-galactoside structure
Common Name 4-methylumbelliferyl α-D-galactoside
CAS Number 38597-12-5 Molecular Weight 338.309
Density 1.5±0.1 g/cm3 Boiling Point 626.9±55.0 °C at 760 mmHg
Molecular Formula C16H18O8 Melting Point 171-173ºC
MSDS USA Flash Point 233.9±25.0 °C

 Use of 4-methylumbelliferyl α-D-galactoside


4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA[1].

 Names

Name 4-Methylumbelliferyl-alpha-D-galactopyranoside hydrate
Synonym More Synonyms

 4-methylumbelliferyl α-D-galactoside Biological Activity

Description 4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA[1].
Related Catalog
In Vitro 4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal) has an emission wavelength of 440 nm and an excitation wavelength of 365 nm[1].
References

[1]. Omid Motabar, et al. High throughput screening for inhibitors of alpha-galactosidase. Curr Chem Genomics. 2010 Dec 3;4:67-73.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 626.9±55.0 °C at 760 mmHg
Melting Point 171-173ºC
Molecular Formula C16H18O8
Molecular Weight 338.309
Flash Point 233.9±25.0 °C
Exact Mass 338.100159
PSA 129.59000
LogP -0.46
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.641
Storage condition 2-8°C
Water Solubility H2O: 10 mg/mL hot, clear, colorless

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+
Risk Phrases R26/27/28
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~%

4-methylumbelliferyl α-D-galactoside Structure

4-methylumbelli...

CAS#:38597-12-5

Literature: Constantzas; Kocourek Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 1099,1102

~%

4-methylumbelliferyl α-D-galactoside Structure

4-methylumbelli...

CAS#:38597-12-5

Literature: Constantzas; Kocourek Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 1099,1102

~%

4-methylumbelliferyl α-D-galactoside Structure

4-methylumbelli...

CAS#:38597-12-5

Literature: Constantzas; Kocourek Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 1099,1102

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 Synonyms

2H-1-Benzopyran-2-one, 7-(α-D-galactopyranosyloxy)-4-methyl-
4-Methyl-2-oxo-2H-chromen-7-yl α-D-galactopyranoside
4-methylumbelliferyl α-D-galactoside
4-METHYLUMBELLIFERYL-α-D-GALACTOPYRANOSIDE
MFCD00063278
EINECS 254-031-1