H-Thr-OMe.HCl

Modify Date: 2024-01-02 11:30:50

H-Thr-OMe.HCl Structure
H-Thr-OMe.HCl structure
Common Name H-Thr-OMe.HCl
CAS Number 39994-75-7 Molecular Weight 169.607
Density N/A Boiling Point 274.4ºC at 760 mmHg
Molecular Formula C5H12ClNO3 Melting Point 64 °C
MSDS USA Flash Point 119.8ºC

 Use of H-Thr-OMe.HCl


H-Thr-OMe.HCl is a threonine derivative[1].

 Names

Name Methyl L-threoninate hydrochloride
Synonym More Synonyms

 H-Thr-OMe.HCl Biological Activity

Description H-Thr-OMe.HCl is a threonine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Boiling Point 274.4ºC at 760 mmHg
Melting Point 64 °C
Molecular Formula C5H12ClNO3
Molecular Weight 169.607
Flash Point 119.8ºC
Exact Mass 169.050568
PSA 72.55000
LogP 0.36980
Storage condition −20°C

 MSDS

Name: l-Threonine methyl ester hydrochloride Material Safety Data Sheet
Synonym:
CAS: 39994-75-7
Section 1 - Chemical Product MSDS Name:l-Threonine methyl ester hydrochloride Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
39994-75-7 L-Threonine methyl ester hydrochloride 254-738-5
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a tightly closed container. Store in a dry area. Deep freeze (below -20C).

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 39994-75-7: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 64 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C5H11NO3.HCl
Molecular Weight: 169.61

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 39994-75-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
L-Threonine methyl ester hydrochloride - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 39994-75-7: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 39994-75-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 39994-75-7 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29225000

 Articles1

More Articles
A versatile chemo-enzymatic route to enantiomerically pure beta-branched alpha-amino acids.

J. Am. Chem. Soc. 126 , 4098-4099, (2004)

A series of diastereoisomers of beta-methyl-beta-phenylalanine analogues 1a-f have been prepared in enantiomerically pure form using a combination of chemo- and biocatalysis. Starting from l-threonine...

 Synonyms

EINECS 254-738-5
Methyl L-threoninate hydrochloride (1:1)
methyl (2S,3R)-2-amino-3-hydroxybutanoate,hydrochloride
L-Threonine, methyl ester, hydrochloride (1:1)
L-Threonine methyl ester hydrochloride
MFCD00037677
AZTREONAM INTERMEDIATES
H-THR-OME·HCL
H-Thr-OMe.HCl
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