L-Threonine

Modify Date: 2026-06-30 16:19:04

L-Threonine Structure
L-Threonine structure
 Common Name L-Threonine
CAS Number 72-19-5 Molecular Weight 119.119
Density 1.3±0.1 g/cm3 Boiling Point 345.8±32.0 °C at 760 mmHg
Molecular Formula C4H9NO3 Melting Point 255ºC
MSDS Chinese USA Flash Point 162.9±25.1 °C

 Use of L-Threonine


L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name L-threonine
Synonym More Synonyms

 L-Threonine Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].
Related Catalog
References

[1]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.3±0.1 g/cm3
Boiling Point 345.8±32.0 °C at 760 mmHg
Melting Point 255ºC
Molecular Formula C4H9NO3
Molecular Weight 119.119
Flash Point 162.9±25.1 °C
Exact Mass 119.058243
PSA 83.55000
LogP -1.23
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.507
InChIKey AYFVYJQAPQTCCC-GBXIJSLDSA-N
SMILES CC(O)C(N)C(=O)O

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XO8590000
CHEMICAL NAME :
Threonine, L-
CAS REGISTRY NUMBER :
72-19-5
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H9-N-O3
MOLECULAR WEIGHT :
119.14
WISWESSER LINE NOTATION :
QY1&YZVQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3098 mg/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81868 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81868 No. of Facilities: 787 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 18524 (estimated) No. of Female Employees: 13980 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS XO8590000
HS Code 29225000

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles339

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u...

Mechanism of chemical activation of sodium chloride in the presence of amino acids.

Food Chem. 166 , 301-8, (2014)

Sodium chloride has been shown to promote chlorination of glycerol during thermal processing. However, the detailed mechanism of this reaction is not well understood. Preliminary experiments have indi...

The unique serine/threonine phosphatase from the minimal bacterium Mycoplasma synoviae: biochemical characterization and metal dependence.

J. Biol. Inorg. Chem. 20(1) , 61-75, (2015)

Serine/threonine protein phosphatases have been described in many pathogenic bacteria as essential enzymes involved in phosphorylation-dependent signal transduction pathways and frequently associated ...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

EINECS 200-774-1
L-Tlhreonine
H-THR-OH
L-Threonine (JP15)
(2S,3R)-(-)-Threonine
L-α-Amino-β-hydroxybutyric acid
L-Threonine
UNII:TFM6DU5S6A
H-L-THR-OH
MFCD00063722
THR
(R-(R*,S*))-2-Amino-3-hydroxybutanoic acid
L-2-Amino-3-hydroxybutyric acid
Threonine
(2S,3R)-Threonine
[R-(R*,S*)]-2-Amino-3-hydroxybutanoic acid
MFCD00064270
(2S,3R)-2-Amino-3-hydroxybutyric acid
QY1&YZVQ &&L or (2S,3R)- Form
(s)-threonine
l-threonin
(2S,3R)-2-Amino-3-hydroxybutanoic acid
l-Thr
Threonin

 L-Threonine | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular weight of L-threonine?
A: Molecular weight of L-threonine is 119.119.
Q: What is the polar surface area (PSA) of L-threonine?
A: Polar surface area (PSA) of L-threonine is 83.55000.
Q: What are the upstream materials of L-threonine?
A: Related upstream materials(CAS) of L-threonine: 4144-02-9;1114-81-4;111610-28-7;34235-88-6;75-07-0;7093-70-1;4378-10-3.
Q: What are the downstream products of L-threonine?
A: Related downstream products(CAS) of L-threonine: 108149-61-7;1492-24-6;3789-59-1;2941-20-0;93-55-0;3228-51-1;5854-78-4;403-42-9;374898-01-8;3373-59-9.
Q: What is the LogP of L-threonine?
A: LogP of L-threonine is -1.23.
Q: What is the InChIKey of L-threonine?
A: InChIKey of L-threonine is AYFVYJQAPQTCCC-GBXIJSLDSA-N.
Q: What is the safety information for L-threonine?
A: Safety information for L-threonine: S24/25.
Q: What are the uses of L-threonine?
A: Main uses of L-threonine: L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].
Q: What is the SMILES notation of L-threonine?
A: SMILES notation of L-threonine is CC(O)C(N)C(=O)O.
Q: What is the CAS number of L-threonine?
A: CAS number of L-threonine is 72-19-5.

 L-Threoninefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
BioBioPha
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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Chemsrc provides L-Threonine(CAS#:72-19-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of L-Threonine are included as well.>> amp version: L-Threonine

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