L-Threonine

Modify Date: 2026-06-30 16:19:04

L-Threonine structure	Common Name	L-Threonine
	CAS Number	72-19-5	Molecular Weight	119.119
	Density	1.3±0.1 g/cm3	Boiling Point	345.8±32.0 °C at 760 mmHg
	Molecular Formula	C₄H₉NO₃	Melting Point	255ºC
	MSDS	Chinese USA	Flash Point	162.9±25.1 °C

Use of L-Threonine

L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	L-threonine
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.3±0.1 g/cm3
Boiling Point	345.8±32.0 °C at 760 mmHg
Melting Point	255ºC
Molecular Formula	C₄H₉NO₃
Molecular Weight	119.119
Flash Point	162.9±25.1 °C
Exact Mass	119.058243
PSA	83.55000
LogP	-1.23
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.507
InChIKey	AYFVYJQAPQTCCC-GBXIJSLDSA-N
SMILES	CC(O)C(N)C(=O)O

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

L-Threonine MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XO8590000

CHEMICAL NAME :: Threonine, L-

CAS REGISTRY NUMBER :: 72-19-5

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C4-H9-N-O3

MOLECULAR WEIGHT :: 119.14

WISWESSER LINE NOTATION :: QY1&YZVQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3098 mg/kg

TOXIC EFFECTS :: Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 10 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81868 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81868 No. of Facilities: 787 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 18524 (estimated) No. of Female Employees: 13980 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XO8590000
HS Code	29225000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 7
CAS#:4144-02-9 O-Methyl-L-threonine CAS#:1114-81-4 threoninium dih... CAS#:111610-28-7 (2R,5S,1'R)-5-(... CAS#:34235-88-6 N-(p-tolylsulfo...
CAS#:75-07-0 ch3cho CAS#:7093-70-1 H-Gly-Thr-OH CAS#:4378-10-3 H-Thr-Obzl.HCl
DownStream 10
CAS#:108149-61-7 4-Methyl 3-(2-m... CAS#:1492-24-6 L(+)-2-Aminobut... CAS#:3789-59-1 ethylbenzylamine CAS#:2941-20-0 1-phenylpropylamine
CAS#:93-55-0 Phenyl ethyl ketone CAS#:3228-51-1 H-Threoninol CAS#:5854-78-4 H-Thr(tBu)-OtBu CAS#:403-42-9 4'-Fluoroacetop...
CAS#:374898-01-8 (R)-1-(4-Fluoro... CAS#:3373-59-9 H-Thr-Ome

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u...

Mechanism of chemical activation of sodium chloride in the presence of amino acids.

Food Chem. 166 , 301-8, (2014)

Sodium chloride has been shown to promote chlorination of glycerol during thermal processing. However, the detailed mechanism of this reaction is not well understood. Preliminary experiments have indi...

The unique serine/threonine phosphatase from the minimal bacterium Mycoplasma synoviae: biochemical characterization and metal dependence.

J. Biol. Inorg. Chem. 20(1) , 61-75, (2015)

Serine/threonine protein phosphatases have been described in many pathogenic bacteria as essential enzymes involved in phosphorylation-dependent signal transduction pathways and frequently associated ...

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

EINECS 200-774-1

L-Tlhreonine

H-THR-OH

L-Threonine (JP15)

(2S,3R)-(-)-Threonine

L-α-Amino-β-hydroxybutyric acid

L-Threonine

UNII:TFM6DU5S6A

H-L-THR-OH

MFCD00063722

THR

(R-(R*,S*))-2-Amino-3-hydroxybutanoic acid

L-2-Amino-3-hydroxybutyric acid

Threonine

(2S,3R)-Threonine

[R-(R*,S*)]-2-Amino-3-hydroxybutanoic acid

MFCD00064270

(2S,3R)-2-Amino-3-hydroxybutyric acid

QY1&YZVQ &&L or (2S,3R)- Form

(s)-threonine

l-threonin

(2S,3R)-2-Amino-3-hydroxybutanoic acid

l-Thr

Threonin

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular weight of L-threonine?

A: Molecular weight of L-threonine is 119.119.

Q: What is the polar surface area (PSA) of L-threonine?

A: Polar surface area (PSA) of L-threonine is 83.55000.

Q: What are the upstream materials of L-threonine?

A: Related upstream materials(CAS) of L-threonine: 4144-02-9;1114-81-4;111610-28-7;34235-88-6;75-07-0;7093-70-1;4378-10-3.

Q: What are the downstream products of L-threonine?

A: Related downstream products(CAS) of L-threonine: 108149-61-7;1492-24-6;3789-59-1;2941-20-0;93-55-0;3228-51-1;5854-78-4;403-42-9;374898-01-8;3373-59-9.

Q: What is the LogP of L-threonine?

A: LogP of L-threonine is -1.23.

Q: What is the InChIKey of L-threonine?

A: InChIKey of L-threonine is AYFVYJQAPQTCCC-GBXIJSLDSA-N.

Q: What is the safety information for L-threonine?

A: Safety information for L-threonine: S24/25.

Q: What are the uses of L-threonine?

A: Main uses of L-threonine: L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

Q: What is the SMILES notation of L-threonine?

A: SMILES notation of L-threonine is CC(O)C(N)C(=O)O.

Q: What is the CAS number of L-threonine?

A: CAS number of L-threonine is 72-19-5.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

BioBioPha

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: L-Threonine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

BioBioPha
China
Product Name: L-Threonine
Price: ￥Inquiry/5mg
Purity: 98.0%
Delivery: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: L-Threonine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: L-threonine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: L-Threonine
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

Get all suppliers and price by the below link:

L-Threonine suppliers

Price: ￥48/25g

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L-Threonine

Use of L-Threonine

Names

L-Threonine Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles339

Synonyms

L-Threonine | FAQ

L-Threoninefactory

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.