Squamolone

Modify Date: 2026-01-29 11:45:37

Squamolone Structure
Squamolone structure
Common Name Squamolone
CAS Number 40451-67-0 Molecular Weight 128.12900
Density 1.353g/cm3 Boiling Point 250.7ºC at 760 mmHg
Molecular Formula C5H8N2O2 Melting Point 143-144 °C
MSDS N/A Flash Point 105.4ºC

 Names

Name 2-oxopyrrolidine-1-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.353g/cm3
Boiling Point 250.7ºC at 760 mmHg
Melting Point 143-144 °C
Molecular Formula C5H8N2O2
Molecular Weight 128.12900
Flash Point 105.4ºC
Exact Mass 128.05900
PSA 63.40000
LogP 0.32570
Index of Refraction 1.551
InChIKey XYVMBSCIEDOIJQ-UHFFFAOYSA-N
SMILES NC(=O)N1CCCC1=O

 Safety Information

HS Code 2933790090

 Synthetic Route

~73%

Squamolone Structure

Squamolone

CAS#:40451-67-0

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Literature: Agrawal, Sumit K.; Sathe, Manisha; Kaushik, M. P.; Halve, A. K. Tetrahedron Letters, 2012 , vol. 53, # 45 p. 5996 - 5999,4 Title/Abstract Full Text Show Details Agrawal, Sumit K.; Sathe, Manisha; Halve; Kaushik Tetrahedron Letters, 2012 , vol. 53, # 45 p. 5996 - 5999

~54%

Squamolone Structure

Squamolone

CAS#:40451-67-0

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Literature: Cytec Technology Corp. Patent: US6630599 B1, 2003 ; Location in patent: Page/Page column 12 ;

~67%

Squamolone Structure

Squamolone

CAS#:40451-67-0

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Literature: Avetisyan, S. A.; Korachov, S. L.; Azaryan, L. V.; Karapetyan, A. A.; Struchkov, Yu. T. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 1 p. 28 - 32 Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 1 p. 33 - 38

~99%

Squamolone Structure

Squamolone

CAS#:40451-67-0

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Literature: Katagiri; Muto; Nomura; Higashikawa; Kaneko Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 5 p. 1112 - 1122

~46%

Squamolone Structure

Squamolone

CAS#:40451-67-0

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Literature: Marquez, Victor E.; Kelley, James A.; Driscoll, John S. Journal of Organic Chemistry, 1980 , vol. 45, # 26 p. 5308 - 5312

~19%

Squamolone Structure

Squamolone

CAS#:40451-67-0

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Literature: Sahai, Mahendra; Srivastava, Anjani; Jamal, Parveen; Sinha, Subhash C.; Singh, Ajay P.; Fujimoto, Yoshinori Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 5 p. 510 - 511

 Customs

HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

 SquamoloneBioassay

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Name: A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in S...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS704
Name: Cytotoxicity against human HepG2 cells
Source: ChEMBL
Target: HepG2
External Id: CHEMBL944430
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Inhibition of thrombin-mediated conversion of fibrinogen to fibrin
Source: ChEMBL
Target: Prothrombin
External Id: CHEMBL944432
Name: Cytotoxicity against human HepG2(2.2.15) cells
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL944431
Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
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 Synonyms

N-carbamoylpyrrolidone
pyrrolidone urea
2-oxopyrrolidinecarboxamide
2-Oxo-1-pyrrolidinecarboxamide
squamolone
1-Carbamoyl-2-pyrrolidone
Bio-0328
2-oxo-pyrrolidine-1-carboxylic acid amide
1-carbamoyl-2-pyrrolidinone
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