p-Toluenesulfonyl isocyanate

Modify Date: 2025-08-20 19:23:32

p-Toluenesulfonyl isocyanate Structure
p-Toluenesulfonyl isocyanate structure
Common Name p-Toluenesulfonyl isocyanate
CAS Number 4083-64-1 Molecular Weight 197.211
Density 1.3±0.1 g/cm3 Boiling Point 288.8±9.0 °C at 760 mmHg
Molecular Formula C8H7NO3S Melting Point 5°C
MSDS Chinese USA Flash Point 128.5±18.7 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

 Names

Name Tosyl Isocyanate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 288.8±9.0 °C at 760 mmHg
Melting Point 5°C
Molecular Formula C8H7NO3S
Molecular Weight 197.211
Flash Point 128.5±18.7 °C
Exact Mass 197.014664
PSA 71.95000
LogP 2.44
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.566
Water Solubility reacts

 Safety Information

Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger
Hazard Statements H315-H319-H331-H334-H335
Supplemental HS Reacts violently with water.
Precautionary Statements P261-P284-P304 + P340 + P312-P305 + P351 + P338-P342 + P311-P403 + P233
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R14;R36/37/38;R42
Safety Phrases S26-S28-S30-S28A
RIDADR UN 2206 6.1/PG 3
WGK Germany 1
RTECS DB9032000
Packaging Group III
Hazard Class 6.1
HS Code 2929109000

 Synthetic Route

 Customs

HS Code 2929109000
Summary 2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles8

More Articles
Palladium-catalyzed tandem bis-allylation of isocyanates.

Org. Lett. 3(6) , 909-12, (2001)

A tandem bis-allylation of p-toluenesulfonyl isocyanate can be achieved by palladium-catalyzed three-component coupling reaction with allylstannanes and allyl chlorides. A high level of regioselectivi...

Determination of 3-α-hydroxytibolone in human plasma by LC-MS/MS: application for a pharmacokinetic study after administration of a tibolone formulation.

Biomed. Chromatogr. 27(11) , 1457-62, (2013)

A new method was developed for the quantitation of 3-α-hydroxy tibolone, in human plasma, after oral administration of a tablet formulation containing tibolone (2.5 mg). 3-α-Hydroxy tibolone was extra...

Simultaneous determination of diethylene glycol and propylene glycol in pharmaceutical products by HPLC after precolumn derivatization with p-toluenesulfonyl isocyanate.

J. Sep. Sci. 30(16) , 2620-7, (2007)

A simple and reliable HPLC method was developed for the simultaneous quantitative analysis of diethylene glycol (DEG) and propylene glycol (PG) in pharmaceutical products by precolumn derivatization. ...

 Synonyms

MFCD00002030
p-Toluenesulfonyl isocyanate,AcroSeal
Benzenesulfonamide, N-carbonyl-4-methyl-
p-Toluenesulphonyl isocyanate
4-methylbenzene-1-sulfonyl isocyanate
4-Methylbenzenesulfonyl isocyanate
EINECS 223-810-8
4-Methyl-N-(oxomethylene)benzenesulfonamide
Benzenesulfonyl isocyanate, 4-methyl-
Tosyl isocyanate
p-Toluenesulfonyl isocyanate
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