piperaquine phosphate
Modify Date: 2024-01-02 19:32:18
piperaquine phosphate structure
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Common Name | piperaquine phosphate | ||
|---|---|---|---|---|
| CAS Number | 4085-31-8 | Molecular Weight | 535.511 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 721.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C29H32Cl2N6 | Melting Point | 198-200°C (lit.) | |
| MSDS | N/A | Flash Point | 389.9±32.9 °C | |
Use of piperaquine phosphatePiperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin[1][2]. |
| Name | Piperaquine phosphate |
|---|---|
| Synonym | More Synonyms |
| Description | Piperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Piperaquine (10-90 mg/kg; a single i.p.) decreases parasitemia at all of the doses tested in mice[1]. Piperaquine (90 mg/kg; a single i.p.) exhibits the t1/2, apparent clearance, and apparent volume of distribution 17.8 days, 33.5 mg•h/L, 1.55 L/h/kg, and 956 L/kg, respectively, in healthy mice and 16.1 days, 27.3 mg•h/L, 1.9 L/h/kg, and 1,059 L/kg in malaria-infected mice[1]. |
| References |
[2]. Davis TME, et, al. Piperaquine: a resurgent antimalarial drug. Drugs. 2005; 65(1): 75-87. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 721.1±60.0 °C at 760 mmHg |
| Melting Point | 198-200°C (lit.) |
| Molecular Formula | C29H32Cl2N6 |
| Molecular Weight | 535.511 |
| Flash Point | 389.9±32.9 °C |
| Exact Mass | 534.206543 |
| PSA | 38.74000 |
| LogP | 5.15 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.664 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Hazard Codes | Xi |
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| HS Code | 2942000000 |
| Precursor 3 | |
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| DownStream 0 | |
CAS#:109-64-8
CAS#:837-52-5
CAS#:86-98-6| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis[7-chloro- |
| 4,4'-(propane-1,3-diyldipiperazine-4,1-diyl)bis(7-chloroquinoline) |
| Piperaquine tetraphosphate tetrahydrate |
| 7-Chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline |
| Piperaquine |
| piperaquinoline |
| PIRERAQUINE PHOSPHATE |
| 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) |