4-(4-(((2R,3R)-3-(3-Carbamimidoylbenzyl)-4-Methoxy-4-Oxobutan-2-Yl)Carbamoyl)Phenyl)Pyridine 1-Oxide Hydrochloride

Modify Date: 2024-02-05 15:24:10

4-(4-(((2R,3R)-3-(3-Carbamimidoylbenzyl)-4-Methoxy-4-Oxobutan-2-Yl)Carbamoyl)Phenyl)Pyridine 1-Oxide Hydrochloride Structure
4-(4-(((2R,3R)-3-(3-Carbamimidoylbenzyl)-4-Methoxy-4-Oxobutan-2-Yl)Carbamoyl)Phenyl)Pyridine 1-Oxide Hydrochloride structure
Common Name 4-(4-(((2R,3R)-3-(3-Carbamimidoylbenzyl)-4-Methoxy-4-Oxobutan-2-Yl)Carbamoyl)Phenyl)Pyridine 1-Oxide Hydrochloride
CAS Number 409081-12-5 Molecular Weight 482.96
Density N/A Boiling Point N/A
Molecular Formula C25H27ClN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-(4-(((2R,3R)-3-(3-Carbamimidoylbenzyl)-4-Methoxy-4-Oxobutan-2-Yl)Carbamoyl)Phenyl)Pyridine 1-Oxide Hydrochloride


Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (Ki=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa[1].

 Names

Name methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate,hydrochloride
Synonym More Synonyms

  Biological Activity

Description Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (Ki=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa[1].
Related Catalog
Target

IC50: Factor Xa[1]

References

[1]. Eikelboom JW, Weitz JI.Otamixaban in acute coronary syndromes.Lancet. 2009 Sep 5;374(9692):762-4. Epub 2009 Aug 28.  

 Chemical & Physical Properties

Molecular Formula C25H27ClN4O4
Molecular Weight 482.96
Exact Mass 482.17200
PSA 130.73000
LogP 5.20930

 Synonyms

Methyl (2R,3R)-2-(3-amidinobenzyl)-3-((4-(1-oxido-4-pyridinyl)benzoyl)amino)butanoate hydrochloride
4-(4-((2R,3R)-3-(3-carbamimidoylbenzyl)-4-methoxy-4-oxobutan-2-ylcarbamoyl)phenyl)pyridine 1-oxide hydrochloride
Otamixaban hydrochloride [WHO-DD]
Otamixaban hydrochloride
UNII-WL9J31M2HI