2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride
Modify Date: 2024-01-14 13:25:10
![2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride Structure](https://www.chemsrc.com/caspic/393/411208-45-2.png)
2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride structure
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Common Name | 2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 411208-45-2 | Molecular Weight | 345.33000 | |
| Density | N/A | Boiling Point | 426.4ºC at 760 mmHg | |
| Molecular Formula | C16H22Cl2N2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 211.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride |
|---|---|
| Synonym | More Synonyms |
| Boiling Point | 426.4ºC at 760 mmHg |
|---|---|
| Molecular Formula | C16H22Cl2N2S |
| Molecular Weight | 345.33000 |
| Flash Point | 211.7ºC |
| Exact Mass | 344.08800 |
| PSA | 54.56000 |
| LogP | 5.97520 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| HS Code | 2930909090 |
|
~79%
2-[2-[(dimethyl... CAS#:411208-45-2 |
| Literature: Tarkiainen, Jari; Vercouillie, Johnny; Emond, Patrick; Sandell, Johan; Hiltunen, Jukka; Frangin, Yves; Guilloteau, Denis; Halldin, Christer Journal of Labelled Compounds and Radiopharmaceuticals, 2001 , vol. 44, # 14 p. 1013 - 1024 Title/Abstract Full Text Show Details Emond, Patrick; Vercouillie, Johnny; Innis, Robert; Chalon, Sylvie; Mavel, Sylvie; Frangin, Yves; Halldin, Christer; Besnard, Jean-Claude; Guilloteau, Denis Journal of Medicinal Chemistry, 2002 , vol. 45, # 6 p. 1253 - 1258 |
|
~38%
2-[2-[(dimethyl... CAS#:411208-45-2 |
| Literature: Jarkas, Nachwa; McConathy, Jonathan; Voll, Ronald J.; Goodman, Mark M. Journal of Medicinal Chemistry, 2005 , vol. 48, # 13 p. 4254 - 4265 |
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~%
2-[2-[(dimethyl... CAS#:411208-45-2 |
| Literature: Vercouillie, Johnny; Mavel, Sylvie; Galineau, Laurent; Ragusa, Tiziana; Innis, Robert; Kassiou, Michael; Chalon, Sylvie; Dolle, Frederic; Besnard, Jean-Claude; Guilloteau, Denis; Emond, Patrick Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1297 - 1300 |
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~%
2-[2-[(dimethyl... CAS#:411208-45-2 |
| Literature: Vercouillie, Johnny; Mavel, Sylvie; Galineau, Laurent; Ragusa, Tiziana; Innis, Robert; Kassiou, Michael; Chalon, Sylvie; Dolle, Frederic; Besnard, Jean-Claude; Guilloteau, Denis; Emond, Patrick Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1297 - 1300 |
|
~%
2-[2-[(dimethyl... CAS#:411208-45-2 |
| Literature: Huang, Yiyun; Bae, Sung-A; Zhu, Zhihong; Guo, Ningning; Roth, Bryan L.; Laruelle, Marc Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2559 - 2570 |
|
~%
2-[2-[(dimethyl... CAS#:411208-45-2 |
| Literature: Huang, Yiyun; Bae, Sung-A; Zhu, Zhihong; Guo, Ningning; Roth, Bryan L.; Laruelle, Marc Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2559 - 2570 |
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.
J. Med. Chem. 45 , 1253-1258, (2002) A series of diphenyl sulfide derivatives substituted at the 1-, 2'-, and 4'-positions has been synthesized and evaluated for their in vitro affinities at the dopamine, serotonin (SERT), and norepineph... |
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Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.
J. Pharmacol. Exp. Ther. 304 , 81-87, (2003) Serotonin transporter has a key-role in regulation of serotoninergic function, and is involved in numerous neurodegenerative and psychiatric disorders. To obtain an efficient radioactive ligand allowi... |
| dihydrochloride |
| 2-(2'-Amino-4'-methylphenylthio)-N,N-dimethylbenzylamine dihydrochloride |
| 2-(2 inverted exclamation marka-Amino-4 inverted exclamation marka-methylphenylthio)-N,N-dimethylbenzylamine dihydrochloride |
| N,N-dimethyl-2-(2-amino-4-methylphenylthio)benzylamine |
| MADAM dihydrochloride |