2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride

2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride Structure
2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride structure
Common Name 2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride
CAS Number 411208-45-2 Molecular Weight 345.33000
Density N/A Boiling Point 426.4ºC at 760 mmHg
Molecular Formula C16H22Cl2N2S Melting Point N/A
MSDS Chinese USA Flash Point 211.7ºC
Symbol GHS07
GHS07
Signal Word Warning

Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.

J. Med. Chem. 45 , 1253-1258, (2002)

A series of diphenyl sulfide derivatives substituted at the 1-, 2'-, and 4'-positions has been synthesized and evaluated for their in vitro affinities at the dopamine, serotonin (SERT), and norepinephrine transporters. The examination of K(i) values revealed ...

Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.

J. Pharmacol. Exp. Ther. 304 , 81-87, (2003)

Serotonin transporter has a key-role in regulation of serotoninergic function, and is involved in numerous neurodegenerative and psychiatric disorders. To obtain an efficient radioactive ligand allowing the study of this transporter in vitro and in vivo, we s...