Acetyl chloride,2-(4-chlorophenoxy)-

Modify Date: 2024-01-02 17:48:10

Acetyl chloride,2-(4-chlorophenoxy)- Structure
Acetyl chloride,2-(4-chlorophenoxy)- structure
Common Name Acetyl chloride,2-(4-chlorophenoxy)-
CAS Number 4122-68-3 Molecular Weight 205.03800
Density 1.314 Boiling Point 142ºC (17 torr)
Molecular Formula C8H6Cl2O2 Melting Point 18.8ºC
MSDS N/A Flash Point 112.9ºC
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 4-Chlorophenoxyacetyl Chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.314
Boiling Point 142ºC (17 torr)
Melting Point 18.8ºC
Molecular Formula C8H6Cl2O2
Molecular Weight 205.03800
Flash Point 112.9ºC
Exact Mass 203.97400
PSA 26.30000
LogP 2.48420
Index of Refraction n20/D 1.5486(lit.)

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3265 8/PG 2
WGK Germany 3
Packaging Group II
HS Code 2918990090

 Synthetic Route

~99%

Acetyl chloride,2-(4-chlorophenoxy)- Structure

Acetyl chloride...

CAS#:4122-68-3

Literature: ALLERGAN, INC.; EHRING, George, R.; CHAO, Ellen; NG, Herman; TON, Hau; LI, Jia Chian; ADORANTE, Joseph, S.; GARST, Michael, E.; RIND, Howard, B.; HANSEN, Mark, R.; AVEY, JR., Alfred, A.; DOLBY, Lloyd, J.; ESFANDIARI, Shervin; MACKENZIE, Vivian, R.; MARSDEN, Jeremiah, A.; MUCHMORE, David, C. Patent: WO2013/101911 A2, 2013 ; Location in patent: Page/Page column 38 ;

~77%

Acetyl chloride,2-(4-chlorophenoxy)- Structure

Acetyl chloride...

CAS#:4122-68-3

Literature: Zhu, Bing-Yan; Su, Ting; Li, Wenhao; Goldman, Erik A.; Zhang, Penglie; Jia, Zhaozhong Jon; Sacrborough, Robert M. Patent: US2004/72860 A1, 2004 ;

~%

Acetyl chloride,2-(4-chlorophenoxy)- Structure

Acetyl chloride...

CAS#:4122-68-3

Literature: Purohit; Srivastava Journal of the Indian Chemical Society, 1991 , vol. 68, # 3 p. 163 - 165

~%

Acetyl chloride,2-(4-chlorophenoxy)- Structure

Acetyl chloride...

CAS#:4122-68-3

Literature: Chaurasia, Sunita; Srivastava, Savitri D. Journal of the Indian Chemical Society, 1992 , vol. 69, # 1 p. 45 - 46

~%

Acetyl chloride,2-(4-chlorophenoxy)- Structure

Acetyl chloride...

CAS#:4122-68-3

Literature: Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M. Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

More Articles
2-(4-Chloro-phen-oxy)-N'-[2-(4-chloro-phen-oxy)acet-yl]acetohydrazide monohydrate.

Acta Crystallogr. Sect. E Struct. Rep. Online 66(11) , o2829, (2010)

In the title compound, C(16)H(14)Cl(2)N(2)O(4)·H(2)O, the hydrazine and water mol-ecules are both located on twofold axes. The C-N-N-C torsion angle is -72.66 (1)° and the dihedral angle between the t...

Synthesis and properties of 2-amino-3-ethycarbonylthieno [2, 3-b] quinuclidines. Kaminka ME, et al.

Pharmaceut. Chem. J. 21(8) , 568-70, (1987)

One-step synthesis of alpha-chloro acetophenones from acid chlorides and aryl precursors.

Org. Lett. 9(4) , 667-9, (2007)

A direct and efficient method was developed for the preparation of a variety of substituted acetophenone derivatives from readily available arene precursors and acid chlorides. This method has signifi...

 Synonyms

MFCD00000727
EINECS 223-923-2
2-(4-chlorophenoxy)acetyl chloride
(4-Chlorophenoxy)acetyl chloride