N-Desmethyl Galanthamine

Modify Date: 2024-01-02 12:04:00

N-Desmethyl Galanthamine Structure
N-Desmethyl Galanthamine structure
Common Name N-Desmethyl Galanthamine
CAS Number 41303-74-6 Molecular Weight 273.32700
Density 1.309g/cm3 Boiling Point 457.923ºC at 760 mmHg
Molecular Formula C16H19NO3 Melting Point 142-145ºC
MSDS N/A Flash Point 230.744ºC

 Use of N-Desmethyl Galanthamine


N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].

 Names

Name N-Desmethyl Galanthamine
Synonym More Synonyms

 N-Desmethyl Galanthamine Biological Activity

Description N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].
Related Catalog
References

[1]. Bachus R, et al. The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6. Pharmacogenetics. 1999;9(6):661-668.

[2]. Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86.

 Chemical & Physical Properties

Density 1.309g/cm3
Boiling Point 457.923ºC at 760 mmHg
Melting Point 142-145ºC
Molecular Formula C16H19NO3
Molecular Weight 273.32700
Flash Point 230.744ºC
Exact Mass 273.13600
PSA 50.72000
LogP 1.83690
Index of Refraction 1.642

 Safety Information

Hazard Codes T+

 Synonyms

N-Norgalanthamine
N-Demethylgalantamine
Norgalantamine
N-desmethyl galantamine
UNII-2BPQ4IVQ21