2,4-Thiazolidinedione

Modify Date: 2026-06-30 12:28:21

2,4-Thiazolidinedione structure	Common Name	2,4-Thiazolidinedione
	CAS Number	2295-31-0	Molecular Weight	117.13
	Density	1.5±0.1 g/cm3	Boiling Point	178-179 ºC (19 mmHg)
	Molecular Formula	C₃H₃NO₂S	Melting Point	123-126 ºC
	MSDS	Chinese USA	Flash Point	138.7±19.3 °C

Use of 2,4-Thiazolidinedione

2,4-Thiazolidinedione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name	1,3-thiazolidine-2,4-dione
Synonym	More Synonyms

Description	2,4-Thiazolidinedione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	PPARγ 激动剂。胰岛素增敏剂。

Density	1.5±0.1 g/cm3
Boiling Point	178-179 ºC (19 mmHg)
Melting Point	123-126 ºC
Molecular Formula	C₃H₃NO₂S
Molecular Weight	117.13
Flash Point	138.7±19.3 °C
Exact Mass	116.988449
PSA	71.47000
LogP	-0.54
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.577
InChIKey	ZOBPZXTWZATXDG-UHFFFAOYSA-N
SMILES	O=C1CSC(=O)N1

2,4-Thiazolidinedione MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ5775000

CHEMICAL NAME :: 2,4-Thiazolidinedione

CAS REGISTRY NUMBER :: 2295-31-0

BEILSTEIN REFERENCE NO. :: 0110700

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C3-H3-N-O2-S

MOLECULAR WEIGHT :: 117.13

WISWESSER LINE NOTATION :: T5SVMV EHJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 335 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 9,274,1954

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XJ5775000
HS Code	2942000000

Precursor 6
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DownStream 10
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HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Cytotoxicity of thiazolidinedione-, oxazolidinedione- and pyrrolidinedione-ring containing compounds in HepG2 cells.

Toxicol. In Vitro 29 , 1887-96, (2015)

Liver damage occurred in some patients who took troglitazone (TGZ) for type II diabetes. The 2,4-thiazolidinedione (TZD) ring in TGZ's structure has been implicated in its hepatotoxicity. To further e...

Differential cardiovascular outcomes after dipeptidyl peptidase-4 inhibitor, sulfonylurea, and pioglitazone therapy, all in combination with metformin, for type 2 diabetes: a population-based cohort study.

PLoS ONE 10 , e0124287, (2015)

Data on the comparative effectiveness of oral antidiabetics on cardiovascular outcomes in a clinical practice setting are limited. This study sought to determine whether a differential risk of cardiov...

Effects of Various 5,7-Dihydroxyflavone Analogs on Adipogenesis in 3T3-L1 Cells.

Biol. Pharm. Bull. 38 , 1794-800, (2015)

We studied the effects of twelve 5,7-dihydroxyflavone analogs on adipogenesis in 3T3-L1 cells. Among the compounds, luteolin, diosmetin, and chrysoeriol partly inhibited adipogenesis by blocking the a...

Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: ULK1_INH_LUMI_1536_1X%INH PRUN

Name: Inhibition of rabbit GSK3
Source: ChEMBL
Target: Glycogen synthase kinase-3 beta
External Id: CHEMBL920549

Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2

Name: Inhibition of Mycobacterium tuberculosis Uracil-DNA glycosylase using 5' 32P end-labe...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5623086

Name: Antimicrobial activity against Staphylococcus aureus UFPEDA 01 at 300 ug/disk after 2...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL1029430

Name: Inhibition of Mycobacterium tuberculosis Uracil-DNA glycosylase using 5'-FAM-CUUUUUGA...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5623087

Name: Antimicrobial activity against Bacillus subtilis UFPEDA 16 at 300 ug/disk after 24 hr...
Source: ChEMBL
Target: Bacillus subtilis
External Id: CHEMBL1029431

Name: Antimicrobial activity against Serratia marcescens UFPEDA 398 at 300 ug/disk after 24...
Source: ChEMBL
Target: Serratia marcescens
External Id: CHEMBL1029428

Name: Inhibition of alpha-glucosidase (unknown origin)
Source: ChEMBL
Target: Maltase-glucoamylase
External Id: CHEMBL4305658

Name: Antimicrobial activity against Escherichia coli UFPEDA 224 at 300 ug/disk after 24 hr...
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL1029429

Total 22, Current Page 1 of 3

EINECS 218-941-2

2,4-Thiazolidindione

usafek-5496

2,4-dioxothiazolidine

Thiazolidinedione

2,4-Thiazolidinedione

1,3-Thiazolidine-2,4-dione

2-thiazolidin-4-one

2,4-thiazolidinone

thiazolidine-2,4-dione

2,4-Thiazolinedione

4-Hydroxy-1,3-thiazol-2(5H)-one

MFCD00005478

TZD

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2,4-Thiazolidinedione
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,4-Thiazolidinedione
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2,4-Thiazolidinedione
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 2,4-Thiazolidinedione
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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