ACTH (11-24)
Modify Date: 2025-08-22 20:29:20
ACTH (11-24) structure
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Common Name | ACTH (11-24) | ||
|---|---|---|---|---|
| CAS Number | 4237-93-8 | Molecular Weight | 1652.04 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C77H134N24O16 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ACTH (11-24)ACTH (11-24) is a fragment of adrenocorticotrophin, acts as an antagonist of adrenocorticotropic hormone (ACTH) receptor, and induces cortisol release. |
| Name | Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro |
|---|---|
| Synonym | More Synonyms |
| Description | ACTH (11-24) is a fragment of adrenocorticotrophin, acts as an antagonist of adrenocorticotropic hormone (ACTH) receptor, and induces cortisol release. |
|---|---|
| Related Catalog | |
| Target |
Adrenocorticotropic hormone receptor[1] |
| In Vitro | ACTH (11-24) acts as an antagonist of adrenocorticotropic hormone receptor[1]. ACTH (11-24) induces cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells. The maximal cortisol release by ACTH (11-24) is enhanced by forskolin but inhibited by calcium channel blockers[2]. |
| In Vivo | ACTH (11-24) blocks electroacupuncture (EA) anti-edema but not EA anti-hyperalgesia in rats[1]. |
| References |
| Molecular Formula | C77H134N24O16 |
|---|---|
| Molecular Weight | 1652.04 |
| PSA | 649.37000 |
| LogP | 4.81050 |
| InChIKey | WNXWTCYVIHOQAJ-IOSGZJLWSA-N |
| SMILES | CC(C)C(NC(=O)C(CCCCN)NC(=O)C(NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(NC(=O)C1CCCN1C(=O)C(N)CCCCN)C(C)C)C(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)O |
| Storage condition | 2-8℃ |
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Name: Lipolytic activity in rat adipocyte plasma membrane vesicles assessed as fatty acid r...
Source: ChEMBL
Target: Lipid bilayer
External Id: CHEMBL3284806
|
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Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
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Name: Human MC2 receptor (Melanocortin receptors)
Source: IUPHAR-DB
Target: MC2 receptor (Melanocortin receptors) [Homo sapiens]
External Id: 283_Human
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Name: Induction of magnesium accumulation in rat adipocyte plasma membrane vesicles assesse...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3284801
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|
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
|
|
Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
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