(+)-Geodin

Modify Date: 2026-07-01 14:02:33

(+)-Geodin structure	Common Name	(+)-Geodin
	CAS Number	427-63-4	Molecular Weight	399.17900
	Density	1.61g/cm3	Boiling Point	652.1ºC at 760 mmHg
	Molecular Formula	C₁₇H₁₂Cl₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	348.2ºC

Use of (+)-Geodin

Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1)[1].

Summary: (+)-Geodin, also known as methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate, is a fungal metabolite with a CAS number of 427-63-4 and a molecular formula of C17H12Cl2O7. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1)[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> PAI-1 Research Areas >> Infection Research Areas >> Inflammation/Immunology

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.61g/cm3
Boiling Point	652.1ºC at 760 mmHg
Molecular Formula	C₁₇H₁₂Cl₂O₇
Molecular Weight	399.17900
Flash Point	348.2ºC
Exact Mass	397.99600
PSA	99.13000
LogP	2.53370
Vapour Pressure	1.32E-17mmHg at 25°C
Index of Refraction	1.647
InChIKey	LUBKKVGXMXTXOZ-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC(=O)C=C(OC)C12Oc1c(Cl)c(C)c(Cl)c(O)c1C2=O

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

2-(2,6-Dihydrox...

CAS#:2151-16-8

(+)-Geodin

CAS#:427-63-4

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Literature: Fujii; Iijima; Ebizuka; Sankawa Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 1 p. 337 - 340

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 1
CAS#:2151-16-8 2-(2,6-Dihydrox...
DownStream 0

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Antifungal activity against Trichophyton rubrum IBT 29284 at 50 uM after 7 days by mi...
Source: ChEMBL
Target: Trichophyton rubrum
External Id: CHEMBL1960335

Name: Antifungal activity against Trichophyton mentagrophytes IBT 2724 at 50 uM after 7 day...
Source: ChEMBL
Target: Trichophyton mentagrophytes
External Id: CHEMBL1960334

Name: Ratio of griseofulvin IC50 to compound IC50 for human MDA-MB-231 cells
Source: ChEMBL
Target: MDA-MB-231
External Id: CHEMBL1960336

Total 3, Current Page 1 of 1

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Geodin

Erdin (+)-form methyl ester

Estin

methyl 5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-3h-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-2'-carboxylate

AmbotzLS-1134

d-Geodin

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the boiling point of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: Boiling point of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate is 652.1ºC at 760 mmHg.

Q: What is the CAS number of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: CAS number of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate is 427-63-4.

Q: What English synonyms does methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate have?

A: English synonyms of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate: Geodin, Erdin (+)-form methyl ester, Estin, methyl 5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-3h-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-2'-carboxylate, AmbotzLS-1134, d-Geodin.

Q: What are the uses of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: Main uses of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate: Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1)[1].

Q: What is the polar surface area (PSA) of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: Polar surface area (PSA) of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate is 99.13000.

Q: What are the upstream materials of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: Related upstream materials(CAS) of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate: 2151-16-8.

Q: What is the molecular weight of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: Molecular weight of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate is 399.17900.

Q: What is the molecular formula of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: Molecular formula of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate is C17H12Cl2O7.

Q: What is the English name of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: The English name of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate is methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate.

Q: What is the SMILES notation of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate?

A: SMILES notation of methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate is COC(=O)C1=CC(=O)C=C(OC)C12Oc1c(Cl)c(C)c(Cl)c(O)c1C2=O.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (+)-Geodin
Price: Check
Purity: 98.0%
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Contact: Yang
Email: sales@echemcloud.com

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