TIE-2/VEGFR-2 kinase-IN-4

Modify Date: 2025-08-20 23:00:20

TIE-2/VEGFR-2 kinase-IN-4 structure	Common Name	TIE-2/VEGFR-2 kinase-IN-4
	CAS Number	433224-29-4	Molecular Weight	539.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₁₇F₄N₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TIE-2/VEGFR-2 kinase-IN-4

TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 5.2 nM and 5.1 nM, respectively. TIE-2/VEGFR-2 kinase-IN-4 can be used for the research of angiogenesis[1].

Name	TIE-2/VEGFR-2 kinase-IN-4

Description	TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 5.2 nM and 5.1 nM, respectively. TIE-2/VEGFR-2 kinase-IN-4 can be used for the research of angiogenesis[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	Tie2:5.2 mM (IC50) VEGFR-2:5.1 nM (IC50)
References	[1]. Hasegawa M, et al. Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors. J Med Chem. 2007 Sep 6;50(18):4453-70.

Molecular Formula	C₂₆H₁₇F₄N₅O₄
Molecular Weight	539.44

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TIE-2/VEGFR-2 kinase-IN-4

Use of TIE-2/VEGFR-2 kinase-IN-4

Names

TIE-2/VEGFR-2 kinase-IN-4 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.