Avasopasem manganese

Modify Date: 2024-01-07 06:30:38

Avasopasem manganese Structure
Avasopasem manganese structure
Common Name Avasopasem manganese
CAS Number 435327-40-5 Molecular Weight 479.35
Density N/A Boiling Point N/A
Molecular Formula C21H31Cl2MnN5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Avasopasem manganese


Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer[1].

 Names

Name Avasopasem manganese

 Avasopasem manganese Biological Activity

Description Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer[1].
Related Catalog
In Vivo Avasopasem manganese is an agent intended to interrupt severe oral mucositis pathogenesis, to reduce the duration, incidence, and severity of radiation-induced oral mucositis[1].
References

[1]. Anderson CM, et al. Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer [published correction appears in J Clin Oncol. 2020 Jan 20;38(3):288]. J Clin Oncol. 2019;37(34):3256-3265.

 Chemical & Physical Properties

Molecular Formula C21H31Cl2MnN5
Molecular Weight 479.35