5a-androstane
5a-androstane structure
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Common Name | 5a-androstane | ||
|---|---|---|---|---|
| CAS Number | 438-22-2 | Molecular Weight | 260.457 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 336.0±9.0 °C at 760 mmHg | |
| Molecular Formula | C19H32 | Melting Point | 78-82 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 145.9±12.3 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
Summary: 5α-androstane (5-ALPHA-雄烷) with CAS number 438-22-2 has a molecular formula of C19H32 and a molecular weight of 260.457. It appears as a liquid, with a melting point of 78-82 °C and a boiling point of 336.0±9.0 °C, and a density of 0.9±0.1 g/cm3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 5α-androstane |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 336.0±9.0 °C at 760 mmHg |
| Melting Point | 78-82 °C(lit.) |
| Molecular Formula | C19H32 |
| Molecular Weight | 260.457 |
| Flash Point | 145.9±12.3 °C |
| Exact Mass | 260.250397 |
| LogP | 8.42 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.508 |
| InChIKey | QZLYKIGBANMMBK-UGCZWRCOSA-N |
| SMILES | CC12CCCC1C1CCC3CCCCC3(C)C1CC2 |
| Storage condition | -20℃ |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H336-H351-H373 |
| Precautionary Statements | P261-P281-P305 + P351 + P338 |
| Target Organs | Blood, Central nervous system, Liver |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | T: Toxic; |
| Risk Phrases | 45-23/24/25-36/37/38-43-63 |
| Safety Phrases | S53-S23-S24/25-S36/37 |
| RIDADR | UN 1593 6.1/PG 3 |
| WGK Germany | 3 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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5a-androstane CAS#:438-22-2 |
| Literature: Butenandt; Tscherning Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 229, p. 185,190 Full Text Show Details Heard; McKay Journal of Biological Chemistry, 1939 , vol. 131, p. 371,378 Full Text Show Details Reichstein Helvetica Chimica Acta, 1936 , vol. 19, p. 979,983 |
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5a-androstane CAS#:438-22-2 |
| Literature: Burrows et al. Biochemical Journal, 1937 , vol. 31, p. 950,957 |
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5a-androstane CAS#:438-22-2 |
| Literature: Burrows et al. Biochemical Journal, 1937 , vol. 31, p. 950,957 |
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5a-androstane CAS#:438-22-2 |
| Literature: Burrows et al. Biochemical Journal, 1937 , vol. 31, p. 950,957 |
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5a-androstane CAS#:438-22-2 |
| Literature: Butenandt; Tscherning Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 229, p. 185,190 |
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5a-androstane CAS#:438-22-2 |
| Literature: Kaegi; Miescher Helvetica Chimica Acta, 1939 , vol. 22, p. 683,695 Full Text Show Details Prelog; Ruzicka; Wieland Helvetica Chimica Acta, 1944 , vol. 27, p. 66,69 |
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5a-androstane CAS#:438-22-2 |
| Literature: Reichstein Helvetica Chimica Acta, 1936 , vol. 19, p. 979,983 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 0 | |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
J. Med. Chem. 52 , 7488-502, (2009) 17beta-Hydroxysteroid dehydrogenase type 7 (17beta-HSD7) catalyzes the reduction of estrone (E(1)) into estradiol (E(2)) and of dihydrotestosterone (DHT) into 5alpha-androstane-3beta,17beta-diol (3bet... |
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Novel and efficient synthesis and antifungal evaluation of 2,3-functionalized cholestane and androstane derivatives
Bioorg. Med. Chem. Lett. 20 , 7372-5, (2010) Synthetic modifications of cholesterol and other traditional steroid molecules have become a promising area for the exploration and development of novel antifungal agents, especially with respect to t... |
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[Bioconversion of C19- and C21-steroids with parent and mutant strains of Curvularia lunata].
Prikl. Biokhim. Mikrobiol. 46(2) , 212-20, (2010) Regio- and stereospecificity of microbial hydroxylation was studied at the transformation of 3-keto-4-ene steroids of androstane and pregnane series by the filamentous fungus of Curvularia lunata VKMF... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Aetioallocholane |
| 5α-Androstan |
| 5alpha-Androstane |
| MFCD00067600 |
| (5a)-Androstane |
| (5α)-Androstane |
| Etioallocholane |
| (5R,8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene |
| 5α,14α-Androstane |
| 5a-androstane |
| EINECS 207-116-2 |
| Aetioallocholan |
| 5α-androstane |
| Androstane |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for 5α-androstane? |
| A: Safety information for 5α-androstane: S53-S23-S24/25-S36/37. |
| Q: What English synonyms does 5α-androstane have? |
| A: English synonyms of 5α-androstane: Aetioallocholane, 5α-Androstan, 5alpha-Androstane, MFCD00067600, (5a)-Androstane, (5α)-Androstane, Etioallocholane, (5R,8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene, 5α,14α-Androstane, 5a-androstane, EINECS 207-116-2, Aetioallocholan, 5α-androstane, Androstane. |
| Q: What is the molecular formula of 5α-androstane? |
| A: Molecular formula of 5α-androstane is C19H32. |
| Q: What is the InChIKey of 5α-androstane? |
| A: InChIKey of 5α-androstane is QZLYKIGBANMMBK-UGCZWRCOSA-N. |
| Q: What is the English name of 5α-androstane? |
| A: The English name of 5α-androstane is 5α-androstane. |
| Q: What is the CAS number of 5α-androstane? |
| A: CAS number of 5α-androstane is 438-22-2. |
| Q: What is the molecular weight of 5α-androstane? |
| A: Molecular weight of 5α-androstane is 260.457. |
| Q: What is the SMILES notation of 5α-androstane? |
| A: SMILES notation of 5α-androstane is CC12CCCC1C1CCC3CCCCC3(C)C1CC2. |
| Q: What is the LogP of 5α-androstane? |
| A: LogP of 5α-androstane is 8.42. |
| Q: What are the upstream materials of 5α-androstane? |
| A: Related upstream materials(CAS) of 5α-androstane: 846-46-8;53-43-0;963-74-6;1912-63-6;27741-16-8;6618-43-5;64-19-7;7647-01-0;1429-06-7. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |