α-Synuclein (61-75)
Modify Date: 2025-08-25 01:43:15
α-Synuclein (61-75) structure
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Common Name | α-Synuclein (61-75) | ||
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| CAS Number | 440645-08-9 | Molecular Weight | 1430.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C60H103N17O23 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of α-Synuclein (61-75)α-Synuclein (61-75) is the 61-75 fragment of α-Synuclein. α-Synuclein is an abundant neuronal protein that is highly enriched in presynaptic nerve terminals. α-Synuclein is a potential biomarker for Parkinson's disease (PD)[1][2]. |
| Name | α-Synuclein (61-75) |
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| Description | α-Synuclein (61-75) is the 61-75 fragment of α-Synuclein. α-Synuclein is an abundant neuronal protein that is highly enriched in presynaptic nerve terminals. α-Synuclein is a potential biomarker for Parkinson's disease (PD)[1][2]. |
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| Related Catalog | |
| In Vitro | Lewy bodies containing α-Synuclein are a neuropathological hallmark of PD, and missense mutations in α-Synuclein (A30P, E46K, H50Q, G51D, A53E, A53T), as well as α-Synuclein gene duplications and triplications, appear to cause PD. Moreover, polymorphisms in regulatory elements of the α-Synuclein gene predispose individuals to PD and are linked to an early onset of the disease. The non-Aβ-amyloid component (NAC) region of α-synuclein is relatively hydrophobic and aggregation-prone in human α-Synuclein but not in mouse α-Synuclein nor in the corresponding homologous region of human β-synuclein. Yet, β-synuclein is more homologous to α-synuclein in the N-terminal sequences (74%) than γ-synuclein (67%)[1]. |
| References |
| Molecular Formula | C60H103N17O23 |
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| Molecular Weight | 1430.56 |